Lyrigabalin Capsule 75 mg (Pregabalin)

Adult dose

This medication is administered orally, divided into two doses daily without regard to meals. For neuropathic pain, the starting dose is 150 mg per day and may be increased to 300 mg per day within 3 to 7 days. If needed, it can be further increased to a maximum of 600 mg per day at 7-day intervals. For patients with epilepsy, the starting dose is 150 mg per day, which can be increased to 300 mg per day after one week if necessary.

Child dose

The safety and efficacy of this medication have not been established in children under 12 years of age and adolescents aged 12-17, thus it is not recommended.

This medication may increase the risk of suicidal thoughts or behaviors, so if mood changes or symptoms of depression occur while taking this medication, consult a healthcare provider immediately. Patients with allergies to any ingredients in this medication or have genetic lactose metabolism disorders should not take it. Diabetic patients may find it challenging to control blood sugar due to weight gain, requiring dosage adjustments of blood sugar medications. If swelling occurs around the face or mouth due to hypersensitivity, cease taking the medication immediately. Elderly individuals should be cautious as they are at higher risk of falling or injury due to dizziness or drowsiness. If blurred vision or changes in vision occur, discontinue the medication and consult a healthcare provider. Suddenly discontinuing this medication can lead to withdrawal symptoms such as insomnia, headaches, nausea, anxiety, etc., so it should be tapered off gradually under medical supervision. Patients with a history of substance abuse may have a higher risk of misuse of this medication, so caution is advised during administration. Renal function-impaired patients may require dosage adjustments. Patients with severe heart disease should exercise caution while taking this medication. Concurrent use with central nervous system depressants, such as opioid analgesics, poses a risk of respiratory depression, and caution is warranted. Pregnant women are advised not to take this medication during early pregnancy due to the risk of fetal malformations, and women of childbearing age should use effective contraceptive methods. Breastfeeding women should consider discontinuing breastfeeding or the medication, as it may be excreted in breast milk. It is safest to avoid hazardous activities like driving or operating machinery until dizziness or drowsiness has resolved after taking the medication. In cases of severe skin rash or allergic reactions, cease taking the medication immediately and inform a healthcare provider. In case of overdose, confusion, drowsiness, depression, seizures may occur, requiring immediate emergency treatment. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, consciousness disturbance, visual disturbances, paralysis, urinary changes

Mild side effects

• Dizziness
• drowsiness
• confusion
• disorientation
• irritability
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization

This medication must be stored in a tightly sealed container to protect it from exposure to air or moisture. It is best stored at room temperature, between 15 to 30 degrees Celsius.

Appearance

A hard capsule with a reddish-brown upper part and a white lower part containing white or pale yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle