Opic Tablet (Ofloxacin)

Adult dosage

○ The usual adult dose is 300～600 mg of ofloxacin daily, divided into 2～3 doses. ○ For Hansen's disease, the dose of this medicine is 400～600 mg daily, divided into 2～3 doses. In principle, it should be used in combination with other anti-Hansen's disease medicines. The dose may be adjusted as appropriate according to age and symptoms.

This medication can cause serious side effects such as tendonitis, tendon rupture, peripheral neuropathy, central nervous system complications, and exacerbation of symptoms in myasthenia gravis. If these symptoms occur, discontinue this medication immediately, and it is not to be used in patients with a history of myasthenia gravis. Elderly patients, those with kidney impairment, and those using corticosteroids should be careful due to an increased risk of tendonitis or tendon rupture; particularly, rupture of the Achilles tendon can occur bilaterally and may appear within 48 hours of taking the medication or even months later. This drug can increase the risk of seizures; therefore, it should be used cautiously in patients with a history of epilepsy or central nervous system disorders. Various side effects such as hypersensitivity reactions, liver and kidney function abnormalities, gastrointestinal disturbances, blood abnormalities, neurological and psychiatric symptoms, skin rash have been reported, so patients should consult medical personnel immediately if unusual symptoms appear. This drug is not to be used in pregnant or lactating women, nor in growing children or adolescents. The elderly may require dose adjustments and careful monitoring due to the potential for increased drug concentration from reduced kidney function. This medication can interact with other drugs, so inform your healthcare provider if you are taking any other medications. Adequate hydration is necessary during treatment, and patients should be cautious of symptoms like dizziness while driving or operating machinery. Additionally, avoid excessive exposure to sunlight or artificial ultraviolet light, and if symptoms of photosensitivity arise, discontinue the medication. This drug should be administered slowly when given by intravenous injection and stored out of reach of children.

tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reactions, rash, itching, erythema, edema, fever, heat sensation, vesicles, erythema, phototoxic reactions, hematuria, acute renal failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST, elevated ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, hematochezia, abdominal pain, diarrhea, nausea, vomiting, gastric and abdominal discomfort, cirrhosis, loss of appetite, abdominal pain, dyspepsia, chest pain, thirst, altered taste, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, petechiae, ecchymosis, prolonged prothrombin time, reversible bone marrow suppression, lymphocytopenia, neutropenia, elevated ESR, insomnia, dizziness, headache, seizures, tremors, paresthesia, peripheral nervous disorders, visual disturbances, diplopia, neglect, nystagmus, auditory disturbances, tinnitus, hearing loss, hallucinations, drowsiness, nervousness, sleep disturbances, confusion, anxiety, depression, restlessness, epiphany, delusion, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory dysfunction, balance disorders, ataxia, aphasia, heaviness in the head, skin and mucous membrane syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, Riel syndrome, arthralgia, myalgia, muscle weakness, myositis, weakness, elevated CPK, elevated myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, nosebleed, stridor, fever, cough, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, prolonged QT interval, ventricular tachycardia, dysuria, frequency of urination, urinary retention, anuria, polyuria, hematuria, urinary storage, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, pruritus of the female external genitalia, menstrual irregularities, uterine cramps, female genital rashes, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, fatigue, fever, aortic aneurysm, aortic dissection, heart valve regurgitation, heart valve insufficiency

Store this drug in a tightly closed container that is well-ventilated and ideally at room temperature between 1 to 30 degrees Celsius. This way, the medication can maintain its effectiveness for a longer period.

Appearance

White to slightly yellowish round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle