Dongkwang Prucalopride 1 mg Tablet (Prucalopride Succinate)

Adult dose

This medication is administered orally and can be taken at any time of the day regardless of meals. Adults should take 2 mg once daily. Elderly patients aged 65 and older should start with an initial dose of 1 mg once daily, which may be increased to 2 mg once daily if necessary. Patients with severe renal impairment (GFR < 30 ml/min/1.73 m2) should take 1 mg once daily. Patients with hepatic impairment among those with moderate liver dysfunction should receive 1 mg once daily.

This medication should not be used in certain patients. For instance, individuals who are allergic to this drug's active ingredients or additives should not take it. Patients with severely impaired kidney function or structural problems in their intestines should also avoid this medication. Additionally, it is not suitable for individuals with genetic disorders that affect lactose breakdown. Since this drug is primarily excreted by the kidneys, patients with severely reduced renal function should use it cautiously and at a reduced dose. Patients with other serious conditions affecting the liver, heart, lungs, or nervous system should also use it under careful medical supervision. Caution is advised when using this drug in patients with a history of heart rhythm disorders or ischemic heart disease, as well as in those with severely impaired liver function who should take a reduced dose. Care is also needed when taking this medication with other drugs that may affect heart rhythm. Common side effects that may occur after administration include headache, nausea, diarrhea, and abdominal pain, and these symptoms generally appear in the early stages of treatment and diminish over time. Symptoms such as fatigue, dizziness, palpitations, vomiting, and indigestion have also been reported. If new palpitations occur, it is essential to consult a physician. There is limited experience with the use of this drug during pregnancy, thus it is not recommended, and fertile women should employ effective contraception during treatment. During breastfeeding, this drug may be secreted in breast milk, but it is not recommended although there is a low likelihood of significant effects on infants. It is advisable not to use this drug in children or adolescents under 18 years of age. In case of overdose, symptoms such as headache, nausea, and diarrhea may occur, and since no specific antidote exists, appropriate treatment should be provided according to the symptoms. This medication may cause dizziness or fatigue on the first day of use, so caution should be exercised when driving or operating machinery. Finally, this medication should be stored out of reach of children and kept in its original container away from moisture.

Serious side effects

Chest discomfort, ventricular premature contractions

Mild side effects

• Headache
• nausea
• diarrhea
• abdominal pain
• dizziness
• tremors
• palpitations
• vomiting
• indigestion
• rectal bleeding

This medication should be stored in a container that blocks light and air, and care should be taken to prevent exposure to moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

White to off-white round film-coated tablets

Package unit

28 tablets (14 tablets/PTP * 2)