Nexiten Tablets 40mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. If esophagitis is untreated or symptoms persist, continue for an additional 4 weeks. - Long-term maintenance therapy to prevent recurrence in patients with esophagitis: 20 mg once daily. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis: · 20 mg once daily. If symptoms are not controlled after 4 weeks, further medical attention is necessary. · Once symptoms improve, subsequent symptoms can be managed with 20 mg once daily. · In adults, 20 mg can be administered once daily as needed. For patients at high risk of developing gastric or duodenal ulcers due to nonsteroidal anti-inflammatory drug use, continuous symptom management is not recommended as needed.

Children's dosage

Adolescents aged 12 years and older 1. Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Administer 40 mg once daily for 4 weeks. If esophagitis is untreated or symptoms persist, continue for an additional 4 weeks.

This medication should not be used in certain patients. Patients who are allergic to this medication or any of its components, or who have experienced hypersensitivity reactions to benzimidazole derivatives should not take this medication. Additionally, patients who are allergic to penicillin-based or macrolide antibiotics should not use this medication when combined with amoxicillin or clarithromycin for the eradication of Helicobacter pylori. Patients taking certain heart-related medications or antivirals, as well as nursing women, should also avoid taking this medication. Adverse effects may occur with this medication, so caution is needed. Common gastrointestinal symptoms such as headache, abdominal pain, diarrhea, nausea, and vomiting may occur. Rarely, serious symptoms such as blood disorders, hypersensitivity, and hypomagnesemia have been reported. If symptoms such as myalgia, weakness, or arrhythmia occur, consult a doctor immediately. Regular examinations are necessary with long-term use of this medication. When taking for more than a year, magnesium levels in the blood should be monitored regularly, and since there may be an increased risk of fractures, bone density tests are also recommended. Additionally, if symptoms suggestive of malignancy occur, malignancy must be ruled out before taking this medication. This medication may interact with other drugs, so patients should inform their doctor or pharmacist of any medications they are currently taking. Care should be taken, especially when used with anticoagulants like warfarin, antivirals, anticonvulsants, antidepressants, etc., and dosage adjustments or monitoring may be required. Data on the safety of this medication in pregnancy is limited, so women who are pregnant or planning to become pregnant should consult a healthcare professional before taking this medication. It is recommended that nursing women do not take this medication. In case of overdose, there is no specific antidote, so treatment according to symptoms and general maintenance therapy is required. It should be kept out of reach of children and should not be stored in other containers.

Serious side effects

Urticaria, angioedema, anaphylaxis, shock, severe allergic reactions, jaundice, hepatitis, liver failure, encephalopathy, mucocutaneous skin syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, eosinophilia and systemic symptoms drug reaction (DRESS syndrome), rhabdomyolysis, severe edema, hypocalcemia, hypokalemia, severe hypomagnesemia, severe neurological symptoms (seizures).

Mild side effects

Headache, dizziness, paresthesia, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, renal interstitial nephritis, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, chest pain, facial swelling.

This medication should be stored in a sealed container to prevent exposure to air or moisture. It is important to maintain the storage temperature between 1°C and 30°C.

Appearance

Pink round film-coated tablet

Package unit

28 tablets/box [14 tablets/Alu-Alu×2]