Alendronate Sodium Trihydrate 70 mg Tablets

Adult dose

As Alendronic Acid, take 70 mg once a week in the morning at least 30 minutes before consumption of food, beverages, or other medications, with a sufficient amount of water (170–230 mL). After taking, do not lie down for at least 30 minutes and do not lie down until the first food intake. This medication should not be taken before bedtime or upon waking. If a dose is missed on the scheduled day, take 70 mg the next morning

This medication may irritate the gastric mucosa, so patients with upper gastrointestinal diseases such as gastritis, esophagitis, or esophageal ulcers should be cautious. It should be taken with a sufficient amount of water, and the patient should not lie down for at least 30 minutes after ingestion to reduce the risk of esophageal irritation. If symptoms such as pain or difficulty swallowing in the esophagus or heartburn occur, discontinue use immediately and consult a physician. Patients with diseases that slow esophageal transit, severe renal impairment, hypocalcemia, and pregnant or nursing women should not take this medication. The absorption of this medication may be interfered with if taken with calcium supplements or antacids, so they should be taken at different times. During treatment, it is advisable to ensure adequate intake of calcium and vitamin D, and consider taking supplements if necessary. This medication can rarely cause pain in bones, joints, or muscles, so if symptoms are severe, consult a physician. Rare side effects such as osteonecrosis of the jaw may occur, so patients requiring dental treatment should consult their physician beforehand. Long-term use may lead to low-energy fractures in certain bones, so it is important to consult a physician if persistent pain occurs. Safety for children and adolescents under 18 has not been established, so use should be avoided. Elderly patients can use it, but some elderly may be more sensitive to medications, so caution is needed. Overdose may lead to hypocalcemia, gastrointestinal disturbances, etc., so the prescribed dosage and directions must be strictly followed. Pregnant women should not take this as it may affect the fetus, and it is also advisable for nursing women to refrain from using this medication.

Serious side effects

Hives, angioedema (severe swelling), cold sweat, pallor, difficulty breathing, esophageal stricture, esophageal perforation, severe esophageal adverse reactions, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), jaundice, serious neurological symptoms, severe swelling or urinary abnormalities, symptoms of hypocalcemia, hypocalcemia, extremely severe pain in bones, joints, and/or muscles (incapacitating), osteonecrosis of the jaw, mucocutaneous syndrome, severe skin reactions

Mild side effects

Abdominal pain, nausea, indigestion, constipation, diarrhea, flatulence, acid reflux, esophageal ulcers, vomiting, dysphagia, abdominal bloating, gastritis, musculoskeletal (bone, muscle, or joint) pain, muscle cramps, headache, dizziness, altered taste, rash, itching, hair loss

This medication is sensitive to air and moisture, so it should be kept in a tightly closed container. It is also advisable to store it at a cool temperature between 15 to 30 degrees Celsius.

Appearance

White oval tablet

Package unit

4 tablets/PTP[(4 tablets/PTP packaging (AluAlu)x1)]