Medication info
Candesartan 8 mg Tablets (Candesartan Cilexetil)

Candesartan 8 mg Tablets (Candesartan Cilexetil)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›8mg / 1 tablet
Manufacturer / importer
대웅바이오(주)
Appearance
Light pink, round tablets with a convex shape on both sides
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201906419 · Approved 2019.09.11 · Insurance code 694002610

Summary

Main use
Improvement of essential hypertension and heart failure (left ventricular dysfunction)
Who takes it
Adults · Children
Adult dose
1. Essential Hypertension Adults: The recommended initial and maintenance dose is 8 to 16 mg of Candesartan Cilexetil, taken orally once daily. If blood pressure is not adequately controlled after 4 weeks of treatment at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. The maximum effect is observed within 4 weeks of starting treatment. 2. Heart Failure Adults: The recommended starting dose is 4 mg once daily.
Child dose
Safety and efficacy for adolescents and children under 18 years have not been established.

Ingredients

Manufacturer
대웅바이오(주)

Efficacy & effects

Improvement of essential hypertension and heart failure (left ventricular dysfunction)

  • Essential hypertension
  • heart failure
  • impaired left ventricular contractile function
  • decreased left ventricular ejection fraction
View approved original text

This medication is used to control essential hypertension, which is high blood pressure of unknown origin. It is also effective for patients with heart failure, particularly those with left ventricular ejection fraction of 40% or less. It may help slow the progression of heart failure and improve heart function. It is used as an alternative treatment for patients who are undergoing ACE inhibitor therapy but require additional treatment or cannot tolerate ACE inhibitors well. This medication stabilizes blood pressure and reduces cardiac workload, thus enhancing overall cardiovascular health. Therefore, it is used to treat essential hypertension and heart failure with reduced left ventricular function.

How to take

Adult dose

1. Essential Hypertension Adults: The recommended initial and maintenance dose is 8 to 16 mg of Candesartan Cilexetil, taken orally once daily. If blood pressure is not adequately controlled after 4 weeks of treatment at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. The maximum effect is observed within 4 weeks of starting treatment. 2. Heart Failure Adults: The recommended starting dose is 4 mg once daily.

Child dose

Safety and efficacy for adolescents and children under 18 years have not been established.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during pregnancy, particularly in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be taken by individuals who are allergic to it or its components, women who are pregnant or breastfeeding, patients with severe liver disease or biliary obstruction, certain hereditary angioedema patients, primary aldosteronism patients, or those with lactose intolerance. Elderly individuals, patients with hyperkalemia, liver disease, heart valve disease, ischemic heart disease, or cerebrovascular disorders, patients with renal artery stenosis, those with reduced intravascular blood volume, reduced kidney function, recent kidney transplant recipients, and children and adolescents under 18 years should use this medication with caution. Possible side effects include dizziness, back pain, respiratory infections, and, in rare cases, serious side effects such as blood abnormalities, liver dysfunction, angioedema, rhabdomyolysis, and acute kidney failure. If any abnormal symptoms occur, consult a doctor immediately. Patients with heart failure or reduced kidney function should have their serum potassium and creatinine levels monitored regularly, as well as close observation of blood pressure and renal function. There may be interactions with other antihypertensive agents, potassium-sparing diuretics, and nonsteroidal anti-inflammatory drugs, so if you are taking other medications, be sure to inform your healthcare provider. Women who are planning to become pregnant or may be pregnant should not take this medication, and breastfeeding women should avoid taking it or stop breastfeeding. Safety and efficacy for individuals under 18 years have not been established, so it is advisable not to use it in this age group. For the elderly, there is a risk of excessive blood pressure lowering leading to conditions such as cerebral infarction, so care should be taken when administering. In case of overdose, symptoms such as symptomatic hypotension, dizziness, or rapid heartbeat may occur, and immediate medical attention should be sought for appropriate treatment. This medication should be stored out of reach of children and not transferred to other containers for safety.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema (swelling of the face, lips, tongue, throat), cold sweat, jaundice, paralysis, kidney damage, acute kidney failure, severe rash, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing, respiratory distress, shock, fainting, loss of consciousness

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory infections, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, joint pain, proteinuria, weakness, fever, paresthesia, dyspepsia, gastroenteritis, tachycardia, palpitations, increased creatine kinase (CK), hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, epistaxis, anxiety, depression, drowsiness, rash, increased sweating,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. It is best kept at room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

Light pink, round tablets with a convex shape on both sides

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.