Clarithron Tablet 250 Milligrams (Clarithromycin)

Adult dosage

○ Adults The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, or rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers For 14 days, administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1-14), and omeprazole 40mg once daily for 28 days (days 1-28).

Children's dosage

Children aged 12 years and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used by specific patients. Patients with allergies to the components included in this medication or those who have had allergic reactions to similar antibiotics should not take it. Moreover, patients taking certain medications that may cause heart rhythm disturbances or those with heart-related diseases should refrain from using this medication. Patients with severely impaired liver or kidney function should also avoid this medication, and it is advisable for pregnant or breastfeeding women not to take it. This medication should be used with caution in patients with compromised liver or kidney function, patients with heart disease, the elderly, and patients who are taking other antibiotics or certain medications concurrently. In particular, careful administration is warranted if there are allergies to medications similar to this one or to the dyes contained in this product. Rarely, severe allergic reactions, breathing difficulties, skin rashes, digestive disturbances, liver function abnormalities, kidney function decline, and neurological symptoms may occur while taking this medication. If such symptoms appear, it is essential to stop using the medication immediately and consult a healthcare professional. This medication may interact with other drugs, so it is critical to inform healthcare professionals of any other medications being taken, particularly those metabolized by the liver or affecting the heart. Pregnant or breastfeeding women should not take this medication, and if it is absolutely necessary, consulting with a specialist about stopping breastfeeding is advisable. This medication has not been thoroughly studied in children under 12, so cautious use is required for this age group. Elderly patients may have decreased kidney function, thus requiring dosage adjustments or careful monitoring while using this medication. In cases of overdose, gastrointestinal disturbances or mental symptoms may occur, hence adherence to prescribed dosages is crucial. In case of overdose, seek medical attention immediately. This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and should ideally be kept at room temperature between 1°C and 30°C.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, hepatic dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, hearing loss, parathesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, auditory impairment, hypoglycemia, rhabdomyolysis, death, purpuric rash, venous thrombophlebitis at injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, mental alterations, obsessive behavior, hypokalemia, hypoxemia

This medication should be stored in a tightly sealed container to prevent air or moisture entry and is best stored at room temperature between 1°C and 30°C.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle