Memantine Tablets (Memantine Hydrochloride)

Adult dose

This medication is taken orally once a day and should be taken at the same time every day. If necessary, it can be administered twice a day. Dosage escalation method: The maximum daily dose is 20mg, and to minimize the risk of adverse reactions, increase the dose by 5mg weekly over the first 3 weeks. - First Week (Days 1-7): Administer 5mg per day - Second Week (Days 8-14): Administer 10mg per day - Third Week

This medication should not be used in patients who are allergic to any of its ingredients. It is also not safe to administer to patients with severely impaired liver function or very poor kidney function. Patients with epilepsy or a history of seizures, or those prone to seizures should use this medication with extreme caution. Additionally, co-administration with other NMDA antagonists such as amantadine, ketamine, and dextromethorphan can worsen side effects, so these should not be used together. Patients with conditions that may change urine acidity (pH) or dietary changes should also be closely monitored. There is insufficient data on the use of this medication in patients with recent heart disease or uncontrolled hypertension, so careful judgment is required. When using this medication, side effects such as dizziness, headaches, constipation, drowsiness, and hypertension may occur, so symptoms should be carefully monitored. Mental confusion, hallucinations, and psychotic reactions have been reported infrequently, so if unusual symptoms occur, immediate consultation with healthcare personnel is recommended. Interactions may occur when used with other medications, particularly with levodopa, dopamine drugs, anticholinergic drugs, barbiturate drugs, antipsychotic medications, skeletal muscle relaxants, and warfarin, so caution is needed when co-administering. Women who are pregnant or may become pregnant should carefully weigh the risks and benefits of using this medication, and breastfeeding women are advised to discontinue breastfeeding while using this medication. Safety has not been established in children or adolescents under 18 years of age, so use in this population is not advisable. In the case of overdose, symptoms of central nervous system effects and gastrointestinal symptoms may occur, so immediate hospital visit for proper treatment is necessary. This medication may decrease the patient's responsiveness, affecting driving or operation of machinery; therefore, caution is advised when engaging in such activities. Lastly, it should be stored out of the reach of children, and it is important not to transfer it to other containers to maintain quality.

Serious side effects

• Seizures
• heart failure
• venous thrombosis/thromboembolism
• respiratory distress

Mild side effects

• Dizziness
• headaches
• constipation
• drowsiness
• hypertension
• confusion
• hallucinations
• psychotic responses
• balance disorders
• gait disturbances

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the drug for a longer period.

Appearance

White, rectangular film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle