Dutasteride Tablet 0.5mg (Dutasteride)

Adult dose

The recommended dose is 1 tablet (0.5 mg) once daily. Swallow this medicine whole without chewing or splitting it. It may be taken with or without food. Dose adjustment is not necessary in patients with renal impairment or in elderly patients. Since there are no data on the use of this medicine in patients with hepatic impairment, the recommended dose for these patients has not been established.

This medication can be absorbed through the skin, so women who are pregnant or may become pregnant should not handle or come into direct contact with it. Handling broken or crushed pieces of this medication may be particularly dangerous. This medication should not be used in children under 18 years old, and it is not to be administered to women. Administration should be avoided in case of allergy to this medication or similar components. Adult men planning to conceive should use this medication cautiously as it may affect reproductive ability, under the guidance of a physician. Patients with high residual urine volume or severe reduction in urine flow should be monitored closely for urinary retention when using this medication. Patients with liver dysfunction should use this medication cautiously as it may affect its metabolism and excretion processes. When taken with strong CYP3A4 inhibitors, this medication's blood concentration may increase; thus, patients who chronically take these drugs should be particularly cautious when using this medication. The most common side effect of this medication is sexual dysfunction, including erectile dysfunction, decreased libido, and ejaculation disorders, which may persist even after discontinuation. Additionally, some patients may experience adverse reactions such as headaches, gastrointestinal discomfort, breast tenderness, or gynecomastia. During medication, regular blood tests should be conducted to check the prostate-specific antigen (PSA) levels, which may decrease after taking this medication; therefore, this should be considered when interpreting test results. This medication may increase the risk of high-grade prostate cancer, so patients should be regularly evaluated for prostate cancer risk. This medication may raise the risk of heart failure; however, an overall increase in the incidence of cardiovascular adverse reactions has not been reported so far. Patients taking this medication should not donate blood, and it is permissible to donate blood only after at least 6 months after the last dose. There is no specific antidote for overdose; thus, appropriate supportive treatment should be provided if symptoms are suspected. This medication should be kept out of the reach of children and stored in its original container to prevent misuse or deterioration in quality. It is known not to affect the ability to drive or operate machinery, but individual responses may vary, so caution is necessary. Patients taking this medication must inform healthcare professionals immediately if they notice any lumps in the breasts or unusual secretions. Finally, this medication should not be administered to women, and its use is not recommended in breastfeeding women.

• Erectile dysfunction
• decreased libido
• ejaculation disorders
• gynecomastia
• headache
• gastrointestinal discomfort and pain
• sexual dysfunction
• breast disorders
• dizziness
• rash

This medication should be stored in a sealed container that prevents air ingress, ideally at room temperature between 1 to 30 degrees Celsius. Storing it in this manner helps maintain its effectiveness and prevents deterioration.

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets (10 tablets/PTP x 3)