Medication info
Levofloxacin 500 mg (Levofloxacin Hemihydrate)

Levofloxacin 500 mg (Levofloxacin Hemihydrate)

Prescription medicationTablet경구
Ingredient · strength
Levofloxacin Hydrate›512.3mg / 1 tablet
Manufacturer / importer
일성아이에스(주)
Appearance
Pink, oblong film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201906213 · Approved 2019.09.02 · Insurance code 655404710

Summary

Main use
Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.
Who takes it
Adults
Adult dose
For adults, levofloxacin is typically taken orally once daily at a dosage of 250–750 mg. For patients with normal renal function, the dosage and duration of treatment based on the indication are as follows: - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10–14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10–14 days - Chronic bacterial prostatitis: 28 days

Ingredients

Manufacturer
일성아이에스(주)

Efficacy & effects

Treatment of complicated skin and soft tissue infections, community-acquired pneumonia, etc.

  • Complicated skin and soft tissue infections
  • community-acquired pneumonia
  • acute bacterial exacerbation of chronic bronchitis
  • acute sinusitis
  • chronic bacterial prostatitis
  • acute pyelonephritis
  • complicated urinary tract infections
  • uncomplicated urinary tract infections
View approved original text

This medication is a broad-spectrum antibiotic effective against various bacterial infections, used for the treatment of complicated skin and soft tissue infections, community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, urinary tract infections, and chronic bacterial prostatitis. However, it is recommended to use this fluoroquinolone antibiotic primarily when there are no other treatment options available due to the risk of serious side effects associated. Therefore, careful usage under the prescription and supervision of a physician is essential. The appropriate treatment method will be determined based on the patient's condition.

How to take

Adult dose

For adults, levofloxacin is typically taken orally once daily at a dosage of 250–750 mg. For patients with normal renal function, the dosage and duration of treatment based on the indication are as follows: - Complicated skin and soft tissue infections: 750 mg every 24 hours for 10–14 days - Community-acquired pneumonia: 500 mg every 24 hours for 7 days - Acute bacterial exacerbation of chronic bronchitis: 7 days - Acute sinusitis: 10–14 days - Chronic bacterial prostatitis: 28 days

Precautions

This medication may cause tendon problems such as tendinitis or tendon rupture, so if there is pain or inflammation in the tendons, use should be stopped immediately. Peripheral neuropathy may occur, and if there are symptoms such as numbness, tingling, or sensory abnormalities in the hands or feet, stop taking the medication and consult a doctor. It can affect the central nervous system, leading to symptoms such as dizziness, anxiety, tremors, or seizures, so report any such symptoms immediately. Patients with myasthenia gravis may experience worsening symptoms if this medication is taken, thus it is advisable not to use it. This medication is intended for specific infections and should only be administered when no other treatment options are available. Elderly patients, patients with reduced kidney function, and those taking corticosteroids are at higher risk for tendon rupture and should be cautious. Do not use in pregnant women, those who may become pregnant, nursing mothers, or adolescents under the age of 18 during their growth period. Severe allergic reactions may occur, so if symptoms such as rash, difficulty breathing, or swelling of the face arise, stop taking the medication immediately. This medication may increase sensitivity to sunlight; thus, avoid strong sunlight or artificial UV exposure and stop use if skin abnormalities occur. Diabetic patients who require blood sugar control should monitor blood sugar levels closely due to possible fluctuations. Be cautious when driving or operating machinery during the use of this medication, as dizziness or drowsiness may occur. There are many drug interactions with this medication, especially when taken with anticoagulants, antacids, iron supplements, and theophylline, so consultation with a physician is necessary. In the case of overdose, central nervous system symptoms and cardiac irregularities may appear, requiring immediate medical attention.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headaches, lightning-type headaches, seizures, altered consciousness, visual disturbances, paralysis, coma

Mild side effects

  • Insomnia
  • dizziness
  • headache
  • tremors
  • anxiety
  • depression
  • psychotic reactions
  • restlessness
  • confusion
  • seizures
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  • visual and auditory disturbances
  • taste and smell disorders
  • hallucinations
  • mania
  • sensory abnormalities
  • sensory loss
  • sensory disorders
  • weakness
  • palpitations
  • QT interval prolongation on ECG
  • arrhythmias
  • increased BUN and serum creatinine
  • nausea
  • vomiting
  • abdominal discomfort
  • diarrhea
  • loss of appetite
  • abdominal pain
  • abdominal distension
  • dyspepsia
  • stomatitis
  • glossitis
  • dry mouth

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container as it may be sensitive to air or moisture. Additionally, avoid places that are too hot or too cold, and it is advised to store it at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Pink, oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.