Calop 2mg (Prucalopride Succinate)

Adult dose

This medication is taken orally and can be administered at any time during the day, regardless of meals. Adults should take 2mg once daily. For patients over 65 years of age, the initial dose is 1mg once daily, which may be increased to 2mg once daily as needed. For patients with severe renal impairment (GFR < 30 ml/min/1.73 m2) and severe hepatic impairment (Child-Pugh class C), the dose is once daily 1mg.

This medicine should not be used by individuals who are allergic to the active ingredient or additives. Patients with severely impaired kidney function or those requiring dialysis should not take this medication. It should also be avoided by patients with bowel perforation or obstruction, or those with severe gastrointestinal diseases such as Crohn's disease or severe colitis. This medication contains lactose and is not suitable for individuals with lactose intolerance or certain genetic metabolic disorders. Patients with severely reduced kidney function should use this medication cautiously with a reduced dose. Special caution is required for patients with other serious conditions affecting the liver, heart, lungs, or nervous system. Individuals with a history of cardiac rhythm disorders or ischemic heart disease should also take care when using this medication. It is recommended to reduce the dose in patients with severely impaired liver function. Care should be taken when taking this medicine together with other drugs that may affect heart rhythms. Common gastrointestinal symptoms that may occur include headaches, abdominal pain, nausea, and diarrhea, usually appearing early in treatment and improving over time. Symptoms such as palpitations, dizziness, and fatigue have also been reported. It is advisable to consult with healthcare professionals if these symptoms appear. Severe diarrhea can reduce the effectiveness of oral contraceptives, so additional contraceptive methods should be used. The potential for interactions with other medications is generally low, but caution is advised when taken with certain potent medications, as blood concentration may change, especially when combined with drugs that affect the heart. There is limited experience with the use of this medication during pregnancy, and it is not recommended for use during this period; women of childbearing age should use effective contraceptive methods. This medication is also not recommended for breastfeeding women. It is advisable not to use this medication in children or adolescents under 18 years of age. In case of overdose, symptoms such as headaches, nausea, and diarrhea may occur, and appropriate treatment should be provided according to the symptoms. This medication may cause dizziness or fatigue at the beginning of treatment, so caution is needed when driving or operating machinery. This medicine should be stored out of the reach of children and kept in its original container away from moisture.

Serious side effects

• Chest discomfort
• ventricular ectopic beats
• chest tightness

Mild side effects

• Headache
• nausea
• diarrhea
• abdominal pain
• dizziness
• tremor
• palpitations
• vomiting
• dyspepsia
• rectal bleeding

This medication should be stored in a container that prevents light and air exposure, and it should be protected from moisture. The recommended storage temperature is between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu * 2)