Medication info

Mapharam Granules

OTC medication경구
Ingredient · strength
Citrus Unshiu Peel Dried Extract (5→1)›68mg / 1 packetAcetaminophen›380mg / 1 packetDL-Methylephedrine Hydrochloride›12.5mg / 1 packetChlorpheniramine Maleate›2.5mg / 1 packetNoscapine›15mg / 1 packetCaffeine Hydrate›30mg / 1 packet
Manufacturer / importer
삼익제약(주)
Appearance
Light brown granules
Packaging
5 sachets/box
Approval status
Active

MFDS item code 201906113 · Notified 2019.08.28

Summary

Main use
Relief of cold symptoms (such as runny nose and nasal congestion)
Who takes it
Adults · Children
Adult dose
Adults aged 15 years and older should take 1 sachet 30 minutes after meals, three times a day.
Child dose
For children aged 11 to under 15 years, take 2/3 sachet once. For children aged 7 to under 11 years, take 1/2 sachet once. For children aged 3 to under 7 years, take 1/3 sachet once.

Ingredients

Manufacturer
삼익제약(주)

Efficacy & effects

Relief of cold symptoms (such as runny nose and nasal congestion)

  • Runny nose
  • nasal congestion
  • sneezing
  • sore throat
  • cough
  • phlegm
  • chills
  • fever
  • headache
  • joint pain
  • muscle pain
View approved original text

This medication helps alleviate various symptoms caused by the common cold, including runny nose, nasal congestion, sneezing, sore throat, cough, phlegm, chills, fever, headache, joint pain, and muscle pain. It reduces the discomfort associated with colds, aiding patients in recovering quickly. This medicine is effectively used to improve the overall relief of cold symptoms, thus lessening the difficulties in daily life.

How to take

Adult dose

Adults aged 15 years and older should take 1 sachet 30 minutes after meals, three times a day.

Child dose

For children aged 11 to under 15 years, take 2/3 sachet once. For children aged 7 to under 11 years, take 1/2 sachet once. For children aged 3 to under 7 years, take 1/3 sachet once.

Precautions

This medication can put strain on the liver, so individuals who regularly consume more than three alcoholic beverages daily must consult a doctor or pharmacist before using it. If severe rashes, blisters, or allergic reactions occur while taking this medication, discontinue use immediately and consult a professional. Due to the presence of acetaminophen, do not exceed the maximum daily dosage, and do not take it with other acetaminophen-containing medications. The artificial sweetener aspartame in this product may pose a problem for individuals with certain genetic disorders; therefore, those with such conditions should avoid this medication. Individuals with allergies to this medication or its ingredients, those with a history of asthma, infants under 3 months of age, and those currently taking certain antidepressants should not use this medication. Do not take this medication with cough suppressants, other cold medications, or antipyretic analgesics without consulting a doctor or pharmacist beforehand. Especially consult a professional before use if you are a child with chickenpox or influenza, have allergies, or have liver, kidney, or heart conditions, or if you are pregnant or breastfeeding. If symptoms such as rash, vomiting, dizziness, severe allergic reactions, shortness of breath, or jaundice occur during use, immediately stop taking the medication and consult a healthcare provider. Children under 2 years of age should not use this medication except in special circumstances, and when given to children, parental supervision is necessary. Carefully follow the prescribed dosage and duration of use, do not take for extended periods, avoid alcohol during treatment, and due to possible drowsiness, caution is advised when driving or operating machinery. Serious side effects can arise when this medication is used in conjunction with certain other drugs, so if you are taking other medications, be sure to inform your healthcare professional. Finally, keep this medication out of the reach of children, store it in a cool place away from direct sunlight and moisture, and do not transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

  • Hives, severe swelling (edema), chest tightness, cold sweat, paleness → shock (anaphylaxis)
  • Severe rash, blisters, peeling skin, pain in mouth/eyes along with high fever → mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis
  • Difficulty breathing or shortness of breath, coughing along with fever → interstitial pneumonia, asthma
  • Yellowing of skin or eyes (jaundice), extreme lethargy → liver dysfunction

Mild side effects

  • Nausea
  • vomiting
  • loss of appetite
  • constipation
  • edema
  • difficulty urinating
  • thirst
  • dizziness
  • anxiety
  • tremors
Show 1 more
  • insomnia

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

This medication should not be taken with MAO inhibitors (antidepressants, antipsychotics, mood stabilizers, anti-Parkinson medications, etc.), cough suppressants, other cold medications, antipyretic analgesics, sedatives, or oral antihistamines (nasal medications, anti-nausea medications, allergy medications). Patients taking diabetes medications, gout medications, arthritis medications, anticoagulants, steroids, barbiturates, tricyclic antidepressants, and alcohol must consult their doctor or pharmacist.

Food interactions

Do not consume alcohol while taking this medication.

Storage

This medication should be stored in a sealed container to prevent exposure to air or moisture. It is best maintained at room temperature between 1 and 30 degrees Celsius to preserve its effectiveness.

Appearance and packaging

Appearance

Light brown granules

Package unit

5 sachets/box

Questions about this medicine

  • QHow many packets should I give to my three-year-old child?

    Children aged 3 years and older but under 7 years should take 1/3 packet per dose, and children aged 2 years and older but under 3 years should take 1/4 packet per dose, three times daily 30 minutes after meals. If your child is at the age boundary, please check with a pharmacist for the exact dosage.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.