Boryung Levocetirizine Hydrochloride Solution

Adult dosage

Adults and children over 6 years: 5 mg (as levocetirizine hydrochloride, 10 mL as a liquid) taken orally once a day, regardless of meals. For adult patients with renal impairment, the dosage should be adjusted based on renal function (creatinine clearance rate (CLCR (ml/min)): - Mild (50 ≤ CLCR < 80): 1 dose of 5 mg, once a day - Moderate (30 ≤ CLCR < 50): 1 dose of 5 mg, once every 2 days -

Children's dosage

Children over 2 years and under 6 years: 1.25 mg (as a liquid, 2.5 mL) once, orally, twice a day. Children over 1 year and under 2 years: 1.25 mg (as a liquid, 2.5 mL) once, orally, once a day.

This medication should not be used in patients who have had an allergic reaction or hypersensitivity to hydroxyzine or piperazine derivatives. It should not be administered to patients with severely impaired renal function or those undergoing hemodialysis. It is safe to avoid this medication during pregnancy or in women who may become pregnant, as well as in breastfeeding women. It should not be used in infants under 1 year of age, and for children under 6 years, only the liquid form should be administered instead of tablets. The liquid formulation contains maltitol, so it should not be administered to patients congenital fructose intolerance. Patients with renal or hepatic impairment, as well as the elderly, should use this medication with caution because the blood concentration may increase. Taking this medication may cause neurological symptoms such as drowsiness, headache, dizziness, and fatigue, so caution is needed when driving or operating machinery. Gastrointestinal symptoms such as nausea, abdominal pain, and diarrhea may occur; if any unusual symptoms arise, consult a doctor. Rarely, cardiac arrhythmias or hematological adverse reactions may occur, so report any unusual symptoms to medical personnel immediately. Allergic reactions such as photosensitivity, rash, or swelling may occur, so take care if there are any changes in the skin. This medication can cause drowsiness or lethargy, so it is advisable not to take it with alcohol or other central nervous system depressants. There is a risk of urinary retention, so patients with spinal disorders or prostatic hypertrophy should use it with caution. The liquid formulation contains preservatives and sweeteners, which may cause allergic reactions or health issues in some individuals. This medication may interact with other drugs, so always consult a healthcare professional if taking other medications. Pregnant and breastfeeding women should avoid this medication, particularly because there is a potential for the drug to be passed through breast milk. Children and the elderly may have reduced renal function, thus careful dosing and administration are necessary. It is advisable to discontinue this medication before allergy testing, as it may affect test results. In case of overdose, symptoms such as drowsiness or agitation may appear, and since there is no specific antidote, appropriate symptomatic treatment should be received. This medication is not readily removed by hemodialysis; thus, prompt medical attention is necessary in case of overdose.

Serious side effects

• Urticaria
• severe swelling (edema)
• angioedema
• anaphylactic shock
• hypertension
• respiratory distress
• rash

Mild side effects

• Drowsiness
• fatigue
• headache
• numbness
• lethargy
• tiredness
• dizziness
• heaviness in the head
• excitement
• thirst

This medication is sensitive to light, so it should be stored in a tightly sealed container that blocks light. It is also important to store it at room temperature between 1 and 30 degrees Celsius to ensure its safety.

Appearance

Colorless and transparent solution in a plastic bottle

Package unit

500 milliliters/bottle