Withers Cef Capsule (Cefadroxil Hydrate)

Adult dose

1) For urinary tract infections: For uncomplicated lower urinary tract infections (e.g., cystitis), administer 1-2g (potency) of cefadroxil in 1-2 divided doses orally per day. For other urinary tract infections, administer 2g (potency) in 2 divided doses per day. 2) For skin and soft tissue infections: Administer 1g (potency) in 1-2 divided doses orally per day. 3) For pharyngitis and tonsillitis: For pharyngitis or tonsillitis due to beta-hemolytic streptococcal infections, administer 1g (potency) in 1-2 divided doses orally for 10 days.

Child dose

1) For urinary tract infections, skin and soft tissue infections: Administer orally in two divided doses of 30mg (potency) per kg of body weight per day. 2) For pharyngitis and tonsillitis: Administer orally in 1-2 divided doses of 30mg (potency) per kg of body weight per day.

This medication should not be used in patients who have previously taken it and experienced a severe allergic reaction such as shock. It should also be avoided by patients who have had allergic reactions to cephalosporin antibiotics. Patients with infectious mononucleosis should not use this medication. This medication contains lactose, so patients with genetic disorders that affect lactose digestion should avoid taking it. When using this drug, caution is especially required for patients with a history of allergy. Patients who have had allergies to penicillin antibiotics should also be careful. Caution is advised if there is a family history of allergic conditions such as asthma, skin rashes, or hives. Patients with significantly impaired kidney function should use this medication with special caution. Patients who cannot consume sufficient food, elderly individuals, or those in poor general condition should be monitored closely for signs of vitamin K deficiency. Patients with a history of gastrointestinal disorders, particularly those who have had colitis, should also be administered this medication with caution. This drug can rarely cause serious shock reactions, so if any unusual symptoms occur, immediate discontinuation and appropriate treatment are required. If allergic symptoms such as skin rash, hives, facial swelling, itching, or fever occur, the administration should be stopped. Watch for side effects like decreased blood cell count, liver dysfunction, or kidney function deterioration. Gastrointestinal symptoms such as severe colitis or diarrhea, nausea, abdominal pain may occur, and immediate cessation of medication is needed if these symptoms appear. Additionally, if respiratory issues such as cough or difficulty breathing arise, treatment should be discontinued and medical care sought. Oral cavity infections or candidiasis may also occur rarely. Central nervous system symptoms such as dizziness, drowsiness, or headache may be evident, with seizures reported in rare cases. Serious skin reactions, including Stevens-Johnson syndrome, may develop, requiring careful monitoring of the skin condition. Symptoms related to vitamin deficiencies or genital infections, joint pain, etc., may also appear, necessitating vigilance for unusual symptoms. When using this medication, it is advisable to confirm the susceptibility of the bacteria to avoid the development of resistant strains and to use it for the minimal required duration. Investigation of the patient's history is crucial to reduce the risk of hypersensitivity reactions. If an allergic reaction occurs, immediate cessation of the medication and appropriate emergency treatments such as oxygen, intravenous fluids, and epinephrine should be administered. Regular monitoring of blood, kidney, and liver functions is necessary when used long-term. For patients with compromised kidney function, dosage adjustments are required, and if seizures occur, the medication should be stopped, and antiepileptic medication may be utilized if needed. When taken with other medications that may affect the kidneys, this drug increases the risk of kidney function deterioration. Taking it with probenecid may increase the concentration of this drug in the body. The safety of this drug during pregnancy has not been fully established, so women who are pregnant or may become pregnant should carefully consider the benefits and risks before using it. Nursing mothers should also exercise caution when using this drug. Elderly patients may experience side effects more readily due to decreased body functions, so dosage and administration intervals should be adjusted, with close monitoring of their condition. Particularly, the risk of bleeding due to vitamin K deficiency may increase. This drug can affect the results of certain urine tests, so it should be taken into consideration when testing. Finally, while taking this medication, there is a risk of increased sensitivity to sunlight, so it is advisable to take care to protect the skin while outdoors.

Serious side effects

• Shock
• hives
• anaphylaxis
• cholestasis
• acute renal failure
• severe colitis
• respiratory distress
• interstitial pneumonia
• eosinophilic lung infiltration
• Stevens-Johnson syndrome

Mild side effects

• Rash
• erythema
• facial swelling
• angioedema
• mucous membrane vesicles
• itching
• fever
• thrombocytopenia
• granulocytopenia
• agranulocytosis

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

Capsule with a red upper part and a yellowish lower part containing white to light yellow powder.

Package unit

30 capsules/bottle, 300 capsules/bottle