Taspen Injection (Acetaminophen)

Adult administration

Adults weighing 50 kg or more 4 times a day, 1000 mg as acetaminophen for a single dose, with a minimum interval of 4 hours. The maximum daily dosage should not exceed 4 grams. Children weighing more than 33 kg and adults weighing less than 50 kg Administer approximately 15 mg/kg as acetaminophen (this drug 1.5 ml/kg) for a single dose, with a minimum interval of 4 hours. The maximum daily dose is 60 mg/kg or should not exceed 4 grams.

Child administration

Children weighing 33 kg (about 11 years) or more Administer approximately 15 mg/kg as acetaminophen (this drug 1.5 ml/kg) for a single dose, with a minimum interval of 4 hours. The maximum daily dose is 60 mg/kg.

This medication can lead to serious poisoning or death due to confusion between milligrams and milliliters during dosing, so it is essential to confirm the correct dosage and administer with caution. Once oral medication can be taken, it is advisable to switch to an appropriate analgesic as soon as possible. Be sure to check if acetaminophen is included in other medications to avoid excessive dosing. Exceeding the recommended dosage can cause significant liver damage; therefore, patients with liver function abnormalities or a history of liver disease should use this drug cautiously and consult a doctor beforehand. Moreover, individuals who frequently consume alcohol every day should consult a professional before taking this medication, as there is a risk of liver damage. Very rarely, severe skin reactions can occur after taking this medication; therefore, if a rash or signs of hypersensitivity appear, stop taking it immediately and consult with a healthcare professional. Patients with an allergy to acetaminophen or this medication, or those with peptic ulcers, severe liver, kidney, or heart disorders, or a history of aspirin-induced asthma should not take this medication. Specific patient groups, including those with liver disease, kidney disease, bleeding tendencies, the elderly, pregnant women, nursing mothers, and children should use this drug with caution and consult with a physician as needed. Regular monitoring, such as liver function tests, may be required, and adverse reactions including increased liver enzymes, blood disorders, skin rashes, and hypotension have been reported. There may be interactions when taken with other medications, especially when used concomitantly with probenecid, isoniazid, phenytoin, anticoagulants, etc. This drug does not affect driving or machine operation, but should not be mixed with other medications. During pregnancy, the benefits and risks of this medication should be carefully evaluated before taking it, and while breastfeeding, small amounts may be excreted in breast milk, but reports of adverse reactions are rare. In case of overdose, serious symptoms such as nausea, vomiting, and liver damage may occur, and immediate hospitalization for detoxification treatment is necessary. This medication should not be stored at temperatures above 30 degrees Celsius, should not be refrigerated or frozen, and before use, it is important to check for any foreign materials or discoloration, and any unused solution should be discarded after single use.

Serious side effects

Allergic reactions, shock, agranulocytosis, neutropenia, leukopenia, thrombocytopenia, coma, acute kidney injury, Lyell's syndrome, acute generalized exanthematous pustulosis, toxic epidermal necrolysis, Stevens-Johnson syndrome, thrombocytopenia, fulminant hepatitis, liver necrosis, liver failure, increased liver enzymes, angioedema, anaphylactic shock, anaphylaxis, hypersensitivity reactions requiring discontinuation of treatment, severe liver damage, acute generalized pustular rash, Stephens'

Mild side effects

Fatigue, low blood pressure, increase in liver transaminase levels, neurological disorders, maculopapular rash, injection site reactions, papular eruption, similar to pemphigus reaction, pustular rash, erythema, flushing, itching, rash, urticaria, nausea, vomiting, headache, constipation, sputum, sensory abnormalities, dizziness, hemoglobin reduction, urinary disorders, tachycardia, and metabolic acidosis due to high anion gap

This medication should be stored at room temperature between 1 and 30 degrees Celsius, and it is important to keep it in a tightly sealed container to prevent air or moisture from entering. Storing it this way will help maintain the efficacy of the drug for a longer time and prevent deterioration.

Appearance

A clear, light yellow transparent liquid filled in a colorless and transparent plastic infusion bag

Package unit

100 milliliters/pack, 75 milliliters/pack