Acyclovir Tablet (Acyclovir)

Adult administration

1. Treatment of herpes simplex virus infections - As acyclovir, administer 200 mg five times a day at 4-hour intervals for 5 days; treatment may be extended in cases of severe primary infections. - Severe immunocompromised patients or those with gastrointestinal absorption disorders may increase the single dose to 400 mg or change the route of administration to intravenous. 2. Prevention of herpes simplex infections in immunocompetent patients

Child administration

1. Treatment of herpes simplex infections and prevention of herpes simplex infections in patients with compromised immune function - Ages 2 and above: follow adult dosing. - Under 2 years: administer half the adult dose. - There is currently no definitive data on the prevention of herpes simplex virus infections in patients with normal immune function.

This medication should not be used in patients who have had allergic reactions to this medication, its components, or valacyclovir. Patients with impaired kidney function may experience more side effects, so caution is advised when using this medication. Patients with compromised liver function should also be administered this medication with care, as their liver function may worsen. Extra caution is required for children and infants, and elderly patients are also at higher risk of renal impairment and adverse reactions, necessitating careful monitoring. Severe allergic reactions, such as anaphylactic shock, may rarely occur; thus, if symptoms like low blood pressure, difficulty breathing, or chest tightness occur during administration, stop the treatment immediately and seek appropriate treatment. Skin rashes, fever, blisters, and hives may appear, and in severe cases, serious skin conditions such as Stevens-Johnson syndrome or Lyell syndrome may develop, requiring cessation of treatment upon symptom onset. Symptoms of a mental or neurological nature can include altered consciousness, confusion, hallucinations, seizures, drowsiness, and anxiety; these symptoms may be more frequent in the elderly or those with reduced kidney function. Kidney problems may arise, with symptoms such as renal failure, hematuria, and proteinuria, so it is important to periodically check kidney function. Blood-related abnormalities can manifest as leukopenia, anemia, bleeding, and purpura; notify healthcare providers immediately if such symptoms occur. Liver dysfunction or symptoms of jaundice or hepatitis may appear, necessitating observation for symptoms along with liver function tests. Gastrointestinal symptoms may include gastritis, nausea, vomiting, abdominal pain, and diarrhea, and treatment should be stopped if symptoms are severe. Adequate hydration is necessary while taking this medication, and preventing dehydration is particularly important during high-dose administration. This medication is most effective when given early in the course of illness, so treatment should begin as soon as symptoms appear. Pregnant women or those who may become pregnant should consult a physician regarding the use of this medication, as it may affect the fetus. Lactating women should discontinue breastfeeding during treatment since this medication’s components may pass into breast milk. Overdosage can result in kidney damage and central nervous system symptoms, and therefore, dosage should be strictly adhered to, with immediate contact with a medical facility in the event of overdose. This medication may interact with other drugs; therefore, inform healthcare providers of any concomitant medications.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, hypotension, anaphylactic shock, anaphylactoid reactions, toxic epidermal necrolysis (Lyell syndrome), Stevens-Johnson syndrome (skin and mucosal syndrome), jaundice, altered consciousness, thunderclap headache, seizures, paralysis, severe edema, decreased urine output, renal failure, hypertension, hematuria, pallor, asthma attacks, dyspnea

Mild side effects

• Photosensitivity reactions
• fixed drug eruptions
• rashes
• fever
• blisters
• urticaria-like erythema
• alopecia
• erythema multiforme
• disturbances in consciousness
• spatial disorientation

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature to ensure the effectiveness and safety of the medication.

Appearance

Light blue round tablet

Package unit

30 tablets/bottle, 200 tablets/bottle