Pregabalin Tablet 75 mg (Pregabalin)

Adult dose

This drug is administered orally in divided doses of the total daily dose of pregabalin twice daily, with or without food. 1. Neuropathic Pain 1) Peripheral Neuropathic Pain The starting dose may be 150 mg per day, and can be increased to 300 mg per day after 3 to 7 days. If necessary, the dose can be further increased to a maximum of 600 mg per day at intervals of 7 days. 2) Central Neuropathic Pain The starting dose may be 150 mg per day, and based on individual response and tolerability, the dose can be increased to 300 mg per day after one week. Additionally, the dose can be increased to a target daily dose of 600 mg after another week, if tolerability is not shown at the target dose.

Child dose

Safety and efficacy data are insufficient for children under 12 years of age and adolescents aged 12 to 17 years, so use is not recommended.

This medication may increase the risk of suicidal thoughts or behaviors, so if depression, mood changes, or unusual behavior occurs during treatment, it should be reported to a healthcare provider immediately. Patients with hypersensitivity to this medication or a known allergy to its ingredients should not take it, and those sensitive to certain dyes or lactose should be cautious. Diabetic patients may require adjustment of their blood sugar control medications due to weight gain, so they should consult their doctor. If symptoms of angioedema (swelling around the face or mouth) occur, the medication should be stopped immediately. Elderly patients may experience dizziness, drowsiness, or confusion while taking this medication, so they should exercise caution and avoid dangerous activities during such symptoms. Visual disturbances or changes in vision may occur during treatment, and patients should inform their doctor if these symptoms appear. Discontinuation of use may lead to withdrawal symptoms such as insomnia, headaches, or anxiety, so abrupt cessation should be avoided. Patients with a history of drug abuse may have a higher risk of misuse of this medication, so caution is advised during use, and monitoring for signs of drug misuse is necessary. Patients with impaired kidney function may require dosage adjustments. Patients with severe heart disease should be careful when using this medication, especially those with congestive heart failure. Caution is needed when taking this drug in conjunction with other central nervous system depressants or opioid analgesics, as the risk of respiratory depression may increase. In early pregnancy, there is a risk of congenital malformations to the fetus, so it is advisable to avoid use during pregnancy, and women of childbearing potential should use effective contraception. Lactating women should discuss with their doctor whether to stop breastfeeding or discontinue this medication, as it can be passed into breast milk. Hazardous activities such as driving or operating machinery should be avoided until dizziness or drowsiness has resolved after taking this medication. Severe skin reactions (such as Stevens-Johnson syndrome) may rarely occur, so if any skin abnormalities develop, the medication should be discontinued immediately and medical personnel should be informed. In cases of overdose, symptoms such as drowsiness, confusion, depression, and seizures may occur, so immediate medical attention is required.

Serious side effects

Urticaria, angioedema, facial swelling, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in the oral/ocular mucosa, severe skin reaction, shortness of breath or difficulty breathing, asthma attacks, respiratory problems with cough + fever, respiratory failure, jaundice (yellowing of skin or eyes), severe systemic symptoms

Mild side effects

• Dizziness
• drowsiness
• confusion
• disorientation
• irritability
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is advisable to keep the storage temperature between 1 to 30 degrees Celsius. This storage method will help maintain the drug's efficacy and safety for a longer period.

Appearance

Light blue oval film-coated tablet

Package unit

30 tablets/bottle