Clamentin Duo Syrup (Amoxicillin·Clavulanate Potassium) (7:1)

Adult dose

For recurrent tonsillitis and upper respiratory infections, lower respiratory infections, urinary tract infections, and moderate to severe skin and soft tissue infections, amoxicillin/clavulanate potassium is typically administered as 25 mg/3.6 mg for every kg of body weight, divided into two doses per day. For severe infections, such as otitis media and sinusitis (upper respiratory infections), bronchopneumonia (lower respiratory infections), and urinary tract infections, typically 45 mg/6.4 mg for every kg of body weight, divided into two doses per day.

Child dose

The 7:1 syrup is not suitable for children under 2 months of age. Renally impaired pediatric patients should not use the 7:1 syrup.

This medication contains the artificial sweetener aspartame and should not be used by patients with phenylketonuria, a hereditary disorder requiring phenylalanine intake restriction. It should not be administered to patients with hypersensitivity to beta-lactam components, especially those with a history of serious allergic reactions such as anaphylaxis or Stevens-Johnson syndrome. Patients with infectious mononucleosis or lymphocytic leukemia may have an increased risk of rashes when using this medication and should avoid it. Patients with a history of hepatic dysfunction or jaundice should not use this medication due to the risk of recurrence. This medication contains lactose and should not be administered to patients with lactose intolerance or galactose metabolism disorder. Patients with liver dysfunction or severe renal impairment, those with allergic tendencies, individuals who have difficulty with oral intake, elderly patients, and those in poor general condition should use this medication with caution, as vitamin K deficiency symptoms may appear. This medication may cause various gastrointestinal side effects, so if symptoms such as diarrhea or abdominal pain occur, consult medical personnel immediately. Liver function abnormalities may occur, so liver function tests should be monitored regularly, particularly during long-term administration exceeding 14 days. Severe skin reactions such as a rash, itching, or in severe cases, Stevens-Johnson syndrome, may occur, and if such symptoms appear, administration should be stopped immediately. Hematological abnormalities, renal function issues, and central nervous system symptoms may also occur infrequently, so patient status should be closely monitored. Pregnant women or women who may become pregnant should especially avoid this medication during the first three months, and nursing mothers should exercise caution as it may cause adverse reactions in their infants. The safety of this medication has not been established in premature infants and newborns; therefore, use is not recommended. Elderly patients may experience adverse reactions more easily due to decreased bodily function and should be administered the medication with adjusted doses and intervals. This medication can interact with other drugs; therefore, patients taking other medications must inform healthcare providers and manage accordingly. In the case of suspected overdose, gastrointestinal symptoms, renal failure, and neurological abnormalities may appear; patients should visit medical institutions immediately if suspected. After use, it should be stored in the refrigerator and consumed within 7 days for safety. This medication should only be used for the minimum duration necessary to prevent the development of resistant bacteria, and if hypersensitivity or severe side effects occur, administration should be discontinued immediately, following medical advice.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe allergic reactions (including anaphylaxis, angioedema, anaphylactic shock), high fever with severe rash, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, mucocutaneous syndrome), asthma attacks, respiratory issues accompanied by cough and fever, breathing difficulties (difficulty breathing)

Mild side effects

Diarrhea, indigestion, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal distension, constipation, colonic pain, gastric acid increase, loose stools, dry mouth, candidiasis, non-bloody colitis, rarely occurring acute pancreatitis, hematological adverse reactions (reversible leukopenia, thrombocytopenia, anemia, etc.), mucosal candidiasis, vaginal itching, increased secretions, nervousness, anxiety, behavioral changes, confusion, drowsiness, insomnia, dizziness

This medication should be stored in a sealed container to prevent exposure to air and moisture. Additionally, it is good to store it in a cool, dry place below 25 degrees.

Appearance

A whitish powder with a peculiar smell, used as a syrup that dissolves when used.

Package unit

50 milliliters/bottle