Medication info
Lyrica Capsules 25 mg (Pregabalin)

Lyrica Capsules 25 mg (Pregabalin)

Prescription medicationHard capsule
Ingredient · strength
Pregabalin›25mg / 1 capsule
Manufacturer / importer
한국휴텍스제약(주)
Appearance
Hard capsule with a light yellow upper part and white lower part containing white powder
Packaging
30 capsules/bottle
Approval status
Active

MFDS item code 201905364 · Approved 2019.07.29 · Insurance code 649104530

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive effect in partial epilepsy, improvement of fibromyalgia
Who uses it
Adults · Children
Adult dosage
This medication is pregabalin and should be taken orally in two divided doses per day, regardless of food. 1. Neuropathic Pain - Peripheral neuropathic pain: Starting dose is 150 mg/day, may increase to 300 mg/day after 3 to 7 days, and may further increase to a maximum of 600 mg/day at intervals of 7 days if needed. - Central neuropathic pain: Starting dose is 150 mg/day, may increase to 300 mg/day after 1 week.
Children's dosage
The safety and efficacy data for patients younger than 12 years old and for adolescents aged 12 to less than 17 years is insufficient, so use is not recommended.

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive effect in partial epilepsy, improvement of fibromyalgia

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is effective in relieving peripheral and central neuropathic pain in adults. It is also used as an adjunctive treatment for partial seizures in epilepsy patients, helping to control symptoms. Additionally, it is utilized for the treatment of fibromyalgia, contributing to the improvement of muscle pain and fatigue. Thus, it is used for the alleviation and treatment of symptoms related to various neurological disorders.

Dosage and Administration

Adult dosage

This medication is pregabalin and should be taken orally in two divided doses per day, regardless of food. 1. Neuropathic Pain - Peripheral neuropathic pain: Starting dose is 150 mg/day, may increase to 300 mg/day after 3 to 7 days, and may further increase to a maximum of 600 mg/day at intervals of 7 days if needed. - Central neuropathic pain: Starting dose is 150 mg/day, may increase to 300 mg/day after 1 week.

Children's dosage

The safety and efficacy data for patients younger than 12 years old and for adolescents aged 12 to less than 17 years is insufficient, so use is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so careful observation for depression or mood changes is required during treatment. It should not be taken if allergic to pregabalin or its ingredients. Patients with certain genetic disorders such as lactose intolerance should also avoid this medication. Diabetic patients may require dose adjustments as weight gain could affect blood sugar control. If symptoms of angioedema occur, use should be discontinued immediately, and elderly patients with severe dizziness or drowsiness should be especially cautious. Blurry vision or changes in eyesight may occur, and if these symptoms appear, consultation with a doctor is necessary. Abrupt discontinuation of this medication can lead to withdrawal symptoms such as insomnia, headaches, nausea, and anxiety; therefore, it should be tapered off slowly under a physician's guidance. Patients with a history of substance abuse may be at higher risk of misuse of this medication and should use it cautiously. Patients with pre-existing heart conditions or impaired renal function require careful monitoring and may need dosage adjustments. Caution should be exercised when co-administering with opioids, as the risk of central nervous system depression may increase. During pregnancy, especially in the first trimester, effects on the fetus are possible; therefore, women who are pregnant or planning to become pregnant should consult a doctor and use effective contraception. Women who are breastfeeding should consider discontinuing breastfeeding or consulting a doctor, as this medication can pass into breast milk. Care should be given to activities that require alertness, such as driving or operating machinery, as this medication may cause dizziness or drowsiness. In case of overdose, symptoms may include confusion, drowsiness, and depression, necessitating immediate medical attention; blood dialysis may be required if necessary. This medication should be kept out of reach of children and should not be transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rashes with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, breathlessness or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), excessive lethargy, sudden and severe headaches, lightning-like headaches, seizures, disorientation, visual disturbances, paralysis.

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disturbances in orientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • hyperesthesia
  • restlessness
  • anxiety
  • mood swings
  • emotional blunting
  • emotional elevation
  • difficulty finding appropriate words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • loss of impulse control
  • apathy
  • ataxia
  • motor coordination issues
  • balance disorders
  • memory loss
  • attention deficit
  • memory deficit
  • tremors
  • speech disorders
  • sensory issues
  • sensory loss.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best stored at room temperature between 15 and 30 degrees Celsius, avoiding extreme heat or cold.

Appearance and packaging

Appearance

Hard capsule with a light yellow upper part and white lower part containing white powder

Package unit

30 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.