Omepros ES Tablets 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be taken with liquids such as water, and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive esophagitis: administer 40 mg once daily for 4 weeks - If symptoms persist or are not treated, an additional 4 weeks of administration - Maintenance therapy to prevent recurrence: 20 mg once daily - Symptomatic therapy (in the absence of esophagitis): 20 mg once daily

Children's dosage

Adolescents aged 12 years and older - Treatment of erosive esophagitis: administer 40 mg once daily for 4 weeks - If symptoms persist or are not treated, an additional 4 weeks of administration - Symptomatic therapy (in the absence of esophagitis).

This medication should not be used in certain patients. Patients who are allergic to this medication, its components, or have experienced hypersensitivity to benzimidazole drugs should not take this medication. Furthermore, caution is advised for patients allergic to penicillin or macrolide antibiotics used in treatment for the eradication of Helicobacter pylori. Patients currently taking specific medications, such as terfenadine, cisapride, pimodizone, astemizole, atazanavir, nelfinavir, or rilpivirine should also avoid using this medication. Nursing mothers and patients with a history of myocardial infarction should not use this medication. This medication contains a coloring agent called Yellow No. 5 (Tartrazine), so patients with hypersensitivity or a history of allergy to this ingredient should use it cautiously. Various adverse reactions may occur during the use of this medication. For example, blood-related issues, hypersensitivity reactions, electrolyte imbalances, psychiatric symptoms, neurological symptoms, gastrointestinal disorders, liver function abnormalities, skin rashes, muscle pain, and kidney problems have been reported. Rarely, serious skin reactions or severe adverse effects such as rhabdomyolysis may occur, so patients should consult healthcare professionals immediately if symptoms appear. This medication inhibits gastric acid secretion, which may slightly increase the risk of gastrointestinal infections. Long-term use may increase the risk of fractures, so patients at risk for osteoporosis should have their condition monitored regularly. Additionally, long-term use may lead to hypomagnesemia, and magnesium levels may need to be periodically tested and supplemented as necessary. This medication has a high potential for drug interactions, so special caution is required when taken alongside anticoagulants, anticonvulsants, certain antibiotics, antiviral agents, antidepressants, etc. If patients are taking other medications, they must inform their physician or pharmacist, and should seek consultation immediately if new symptoms arise. Data on the safety of this medication during pregnancy is limited, so it should only be used after adequate consultation with a physician during pregnancy. Nursing mothers are also advised not to take this medication. In case of overdose, there are no specific antidotes, so symptomatic treatment should be administered instead, along with general supportive care. Lastly, this medication should be stored out of the reach of children, and transferring it to other containers is not recommended as it may adversely affect the quality of the medication.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, severe allergic reactions, angioedema, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, DRESS syndrome, mucocutaneous blistering syndrome, severe skin adverse reactions, jaundice, hepatic failure, encephalopathy, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, agranulocytosis, pancytopenia, interstitial nephritis, severe adverse reactions.

Mild side effects

• Leukopenia
• thrombocytopenia
• agranulocytosis
• pancytopenia
• fever
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. The recommended storage temperature is room temperature between 1 and 30 degrees Celsius to maintain the medication's effectiveness.

Appearance

Pale pink round film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)