Medication info
Omape Tablet (Limaprost Alpha-Dex)

Omape Tablet (Limaprost Alpha-Dex)

Prescription medicationTablet
Ingredient · strength
Limaprost Alfadex›166.67μg / 1 tablet
Manufacturer / importer
Hanool BioPharma Co., Ltd.
Appearance
White round tablet
Packaging
84 tablets/box [21 tablets/Alu-AluX4]
Approval status
Active

MFDS item code 201904634 · Approved 2019.07.09 · Insurance code 655605170

Summary

Main use
Improvement of symptoms and walking ability in acquired lumbar spinal stenosis; improvement of ischemic symptoms of Buerger's disease
Who uses it
Adults
Adult dosage
For improvement of ischemic symptoms such as ulcers, pain, and coldness associated with thromboangiitis obliterans (Buerger’s disease), the usual adult dose is 2 tablets orally 3 times daily. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability associated with acquired lumbar spinal canal stenosis (patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted appropriately according to age and symptoms.

Ingredients

Manufacturer
Hanool BioPharma Co., Ltd.

Efficacy & effects

Improvement of symptoms and walking ability in acquired lumbar spinal stenosis; improvement of ischemic symptoms of Buerger's disease

  • Ulcers
  • pain
  • cold sensation
  • subjective symptoms
  • leg pain
  • leg numbness
View approved original text

This medication helps improve ischemic symptoms such as ulcers, pain, and cold sensation caused by occlusive thromboangiitis (Buerger's disease). It is also used to alleviate subjective symptoms such as leg pain and numbness in patients with acquired lumbar spinal stenosis, as well as to improve walking ability.

Dosage and Administration

Adult dosage

For improvement of ischemic symptoms such as ulcers, pain, and coldness associated with thromboangiitis obliterans (Buerger’s disease), the usual adult dose is 2 tablets orally 3 times daily. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability associated with acquired lumbar spinal canal stenosis (patients with a normal SLR test and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. The dose may be adjusted appropriately according to age and symptoms.

Precautions

This medication should not be used in women who are pregnant or may become pregnant. This medication contains lactose, therefore patients with genetic disorders that affect lactose digestion should not take it. Patients with bleeding tendencies or those taking medications that affect blood coagulation should use this medication cautiously. Allergic reactions such as skin rash or itching may occur with this medication; if these symptoms appear, discontinue use immediately. Bleeding can occur rarely, so if bleeding symptoms appear, stop taking the medication and consult a doctor. Gastrointestinal symptoms such as diarrhea, nausea, abdominal pain, loss of appetite, and heartburn may occur, so caution is needed. It may affect liver function, and there may be cases of elevated liver enzymes. Symptoms such as rapid heartbeat, hypotension, and cyanosis of the extremities may appear rarely. Headache, facial flushing, dizziness, heat sensation, trembling, swelling, and other symptoms may occur. Patients with lumbar spinal stenosis should closely monitor changes in symptoms to decide whether to continue taking the medication. Safety during pregnancy has not been established, and uterine contraction effects have been confirmed in animal studies, so pregnant women should not take it. Safety has not been confirmed for pediatric use, so it is advisable not to use it in children. Elderly patients, whose physical function may be decreased, require caution such as dose adjustment.

Side effects

  • Rash
  • itching
  • bleeding
  • diarrhea
  • nausea
  • abdominal discomfort
  • abdominal pain
  • loss of appetite
  • heartburn
  • vomiting
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  • abdominal bloating
  • elevated AST (GOT)
  • elevated ALT (GPT)
  • palpitations
  • peripheral cyanosis
  • hypotension
  • headache
  • facial flushing
  • dizziness
  • fever
  • general malaise
  • edema
  • mammary gland swelling
  • shaking
  • hirsutism
  • anemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. This will help maintain the effectiveness of the medication for a long period.

Appearance and packaging

Appearance

White round tablet

Package unit

84 tablets/box [21 tablets/Alu-AluX4]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.