Hyubis D Tablet

Adult dose

Generally, take 1 tablet orally twice a day in the morning and before bedtime, regardless of meals. 1) Gastric and duodenal ulcers: Take 1 tablet twice a day or 2 tablets once a day before bedtime. Especially for patients with duodenal ulcers, taking 2 tablets twice a day in the morning and before bedtime can lead to a higher treatment success rate. The dosage is the same for prophylactic therapy to prevent ulcers or gastric and duodenal ulcers arising from long-term NSAID use. Usually, conditions due to NSAID use heal within 4 to 8 weeks, although healing duration may be extended in some patients. For recurrent ulcer patients who responded well to short-term therapy with this drug, it may be maintained at a dosage of 1 tablet once a day before bedtime. 2) Gastroesophageal reflux disease: Administer 1 tablet twice a day for 8 weeks or 2 tablets once a day before bedtime. For patients with severe gastroesophageal reflux, the dose can be increased to 2 tablets four times a day. 3) Zollinger-Ellison syndrome: Start treatment with 1 tablet three times a day as the initial dose, and it can be increased if needed. In severe cases, one can prescribe up to 6 g of ranitidine per day based on a physician's instructions. 4) Peptic ulcers, acute stress ulcers, and upper gastrointestinal bleeding due to acute mucosal lesions: Once oral administration is possible, switch from injection to oral and administer 1 tablet twice a day. 5) Pre-anesthetic administration (to prevent Mendelson's syndrome): Administer 1 tablet 2 hours before anesthesia induction. In this case, taking 1 tablet on the night before surgery is also advisable.

This medication should not be used in patients undergoing dialysis or those with impaired kidney function. Patients who have experienced allergic reactions to this medication or its components should also not receive it. Patients with a history of acute porphyria should be cautious as this medication may worsen symptoms. It is not recommended for patients who have undergone gastrointestinal surgery, pregnant women or women who may become pregnant, as well as premature infants or newborns. Patients on a diet restricting potassium intake should also avoid this medication. Caution is required when administering to patients with impaired liver function, a history of drug allergies, the elderly, and those with a history of kidney dysfunction. When taken in conjunction with NSAIDs, particularly elderly patients or those with a history of peptic ulcer should have their conditions monitored regularly. This medication may mask symptoms of gastric cancer, so patients with gastric ulcers or those above middle age experiencing new or changing symptoms of dyspepsia should be evaluated for malignancy before treatment. Patients with Helicobacter pylori-positive gastric and duodenal ulcers require eradication therapy. Patients in severe care units, patients with hypophosphatemia, and those with dysphagia should be careful as side effects may occur after administration of this medication. When using this drug, serious allergic reactions such as shock or hypersensitivity may rarely occur; if unusual symptoms appear, treatment should be stopped immediately, and appropriate medical care should be sought. Blood-related side effects may include rare occurrences of leukopenia, thrombocytopenia, and bone marrow suppression; symptoms should be reported to a healthcare professional immediately. Transitory hepatic abnormalities may occur; if hepatitis symptoms arise, use of the medication should be stopped immediately. Gastrointestinal symptoms such as arrhythmia, nausea, diarrhea, and abdominal pain may appear. Central nervous system side effects such as dizziness, drowsiness, confusion, and seizures may rarely occur, and careful observation is required. Muscle pain or joint pain may indicate side effects, so consultation with healthcare professionals is advised. Skin-related side effects such as rashes or hair loss have also been reported rarely. It is advisable not to use this medication for an extended period, and if treatment effects are lacking, it should be switched to another medication. The elderly, patients with chronic lung disease, diabetes, and those with compromised immunity may face an increased risk of pneumonia and should be cautious. If dizziness or drowsiness occurs, avoid driving or operating dangerous machinery. This medication may interact with other drugs, so especially for those taking anticoagulants or certain antibiotics and anticonvulsants, consultation with healthcare professionals is necessary. It is safest not to use this medication during pregnancy or breastfeeding. Safety in children has not been established, and use is not recommended. In cases of overdose, procedures such as vomiting or gastric lavage may be needed, and in some cases, blood dialysis may be used to remove the drug. This medication reduces gastric acid secretion, which can promote bacterial growth in the gastrointestinal tract, so ocular examinations may be required for prolonged use.

Serious side effects

• Urticaria, angioedema, anaphylactic shock, severe allergic reactions
• Hepatitis, jaundice, liver dysfunction
• Tachycardia, bradycardia, heart block, premature ventricular contractions, arrhythmias
• Seizures, consciousness disturbances, mental confusion, convulsions
• Rhabdomyolysis
• Stevens-Johnson syndrome, toxic epidermal necrolysis
• Acute interstitial nephritis
• General malaise, weakness, mucous membrane bleeding, fever
• Bone marrow suppression, aplastic anemia, aplastic anemia, acquired immune hemolytic anemia
• Respiratory complications

Mild side effects

• Skin rash
• angioedema
• fever
• bronchospasm
• hypotension
• chest pain
• granulocytopenia
• leukopenia
• thrombocytopenia
• elevated serum enzyme levels

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it is important to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help preserve the medication's efficacy for a long time.

Appearance

Light green oblong film-coated tablets

Package unit

For domestic use - 10 tablets/bottle, For domestic use - 30 tablets/bottle, For domestic use - 300 tablets/bottle