Latopu Tablet (Rabeprazole)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. Clinical trial results with treatment for up to 8 weeks showed that most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. Clinical trial results with treatment for up to 6 weeks showed that most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily before bedtime. Clinical trial results with treatment for up to 2 weeks showed that most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine per administration, given orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

This medication should not be used in patients who are allergic to its ingredients. Additionally, it contains lactose, so patients with genetic disorders such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should avoid it. Patients who are allergic or sensitive to soybean oil, soy, or peanuts should not use this medication. Patients with a history of hypersensitivity to drugs, patients with liver or kidney function issues, patients on dialysis, elderly patients, and those with abnormalities in lipid metabolism or requiring caution with lipid emulsions should use this medication with caution. This medication can sometimes cause serious allergic reactions such as anaphylaxis or shock; therefore, if symptoms such as facial pallor, low blood pressure, skin rash, or breathing difficulties occur, you should stop taking it immediately and consult a healthcare provider. Liver function impairment or jaundice may occur, so liver function should be monitored periodically, and if there are abnormal signs, use should be discontinued. There may be a decrease in blood cell counts, especially agranulocytosis or thrombocytopenia, and if initial symptoms such as sore throat, general malaise, or fever appear, you should consult a physician immediately. Additionally, rare but serious side effects such as skin rash, seizures, or heart problems have been reported; therefore, you should inform a healthcare provider immediately if any unusual symptoms occur. Pregnant women or those who may become pregnant should take this medication cautiously under the guidance of a physician, and it is advisable for breastfeeding women not to take this medication. Safety in children has not been sufficiently established, so special caution is required when prescribing to children. This medication should be kept out of the reach of children and stored in its original packaging for safety. Elderly patients may have decreased bodily function, so the dosage and frequency should be adjusted, and their condition should be closely monitored. In dialysis patients, drug concentration in the blood may increase, so it should be administered cautiously starting with a low dose. Symptoms of malignant tumors can be masked while using this medication, so if gastric-related symptoms are severe or suspected, additional tests should be performed to confirm the presence of malignant tumors. Patients at risk of fat overload should monitor their blood lipid levels and adjust the dosage as necessary.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized rash
• shortness of breath
• hepatic dysfunction
• jaundice
• AST (GOT) elevation
• ALT (GPT) elevation

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. Additionally, the storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

300 tablets/bottle, 30 tablets/bottle