Glimepiride Tablet 2 mg (Glimepiride)

Adult dose

Individual adjustments are made for each patient. Swallow without chewing with more than 1/2 cup of water. This medication is taken orally once daily. It should be taken before breakfast or immediately before the first meal. 1. Monotherapy - The initial dose starts at 1 mg of glimepiride, taken once daily. - The dose may be increased by 1 mg every 1-2 weeks. - Generally, doses above 4 mg provide little additional effect.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or coma. Additionally, individuals who have had allergic reactions to this medication or sulfonylureas or sulfonamides should not be administered this medication. In patients with severely impaired liver or kidney function, it is recommended to switch to insulin therapy instead of using this medication. Women who are pregnant or may become pregnant and breastfeeding women should not take this medication. Patients with severe infections, before or after surgery, or those with severe trauma may require insulin therapy, making this medication unsuitable. Conditions like diarrhea or vomiting can affect food absorption, increasing the risk of hypoglycemia. This medication contains lactose, so patients with lactose intolerance or related genetic disorders should avoid taking it. During the initial week of dosing, there is a heightened risk of hypoglycemia, requiring careful monitoring. Particularly, older adults, individuals with poor nutritional status or those who skip meals, those with an imbalance between exercise and food intake, and individuals who consume alcohol frequently are at increased risk of hypoglycemia. Patients with impaired kidney or liver function, as well as those who overdose on this medication, should also be cautious regarding hypoglycemia. Endocrine disorders such as thyroid abnormalities or adrenal insufficiency should also be considered for careful administration. When taking this medication with other drugs, interactions may alter the risk of hypoglycemia, so consultation with a doctor or pharmacist is necessary. Individuals allergic to Yellow No. 4 (Tartrazine) present in this medication should also exercise caution. Symptoms of hypoglycemia may occur while taking this medication, including headache, severe hunger, nausea, fatigue, anxiety, confusion, visual disturbances, dizziness, drowsiness, and reduced consciousness. Hypoglycemia can be rapidly controlled by sugar intake, so it is important to always carry sugar. Temporary blurred vision, gastrointestinal disturbances, liver dysfunction, blood abnormalities, and allergic reactions may occur rarely; symptoms should be promptly reported to healthcare personnel. While taking this medication, regular meals, exercise, and weight management should be practiced, and blood sugar control should be continuously monitored. Teaching patients and their families about the risks and symptoms of hypoglycemia, as well as treatment methods, is essential. Especially in situations of severe stress, surgery, or infection, blood sugar control may become challenging, necessitating a switch to insulin therapy. This medication should not be used during pregnancy or lactation due to potential harm to the fetus and newborn; insulin therapy should be switched if necessary. It is not used in children under 18 years of age as safety and efficacy have not been established. Elderly patients may require dose adjustments due to decreased kidney function. In cases of overdose, severe hypoglycemia may occur, necessitating immediate treatment at a medical institution, with emergency measures such as inducing vomiting, blocking drug absorption, or administering glucose injections if necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• reduced agility or activity

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is best to maintain a storage temperature in the range of 1 degree to 30 degrees Celsius. Storing it this way preserves the effectiveness of the medication.

Appearance

Green rectangular tablet

Package unit

30 tablets/bottle, 100 tablets/bottle