TDicl Tablets (Clarithromycin)

Adult dosage

○ Adults : The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The treatment period is usually 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. ○ Mycobacterial infections : Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, or rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer : Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (Days 1～14), and omeprazole 40mg once daily for 28 days (Days 1～28).

Children's dosage

Children 12 years of age and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be used by individuals allergic to specific components. Persons who have had hypersensitivity reactions to clarithromycin or other similar antibiotics should also avoid it. Patients with heart rhythm issues or significantly decreased liver and kidney function should not use this drug. Serious side effects may occur when combined with certain heart medications or some steroids and statins. Pregnant or breastfeeding women should not take this medication and should consult a doctor if necessary. Various side effects may occur, including gastrointestinal disorders, allergic reactions, liver and kidney function issues, neuropsychiatric symptoms; if unusual symptoms arise, immediate medical attention is required. Long-term use can lead to resistant bacteria, so it is crucial to take it for the necessary duration only. It is important to inform your doctor or pharmacist if you are taking other medications, especially if you have heart, liver, or kidney disease. Special caution is needed for children, the elderly, and immunocompromised patients. In cases of overdose, gastrointestinal disorders and central nervous system symptoms may occur, necessitating immediate medical attention. This medication should be stored in a tightly sealed container away from direct sunlight and should not be refrigerated.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, type of spasm, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, loss of appetite, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, bloody stool, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, loss of appetite, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, malaise, elevated CPK, increased serum and urine myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, lethargy, headache, dysgeusia, hearing loss, paresthesia, joint pain, myalgia, olfactory dysfunction, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute pancreatitis, increased amylase, elevated AST and ALT, leukopenia, thrombocytopenia, elevated ALT, elevated AST, elevated γ-GTP, elevated ALP, elevated LDH, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, phlebitis at injection site, pain at injection site, inflammation at injection site, fever, malaise, chest pain, chills, fatigue, abnormal albumin-globulin ratio, vasodilation, angioedema, anaphylactic reaction, angioedema, loss of appetite, decreased appetite, hypoglycemia, insomnia, anxiety, neuroirritability, shouting, psychotic disorder, state of confusion, depersonalization, depression, disorientation, hallucinations, abnormal dreams, mania, dysgeusia, headache, loss of consciousness, movement disorders, non-vestibular dizziness, drowsiness, tremors, convulsions, loss of taste, abnormal olfaction, loss of smell, vestibular dizziness, hearing impairment, hearing loss, cardiac arrest, atrial fibrillation, QT interval prolongation on ECG, extrasystole, palpitations, Torsades de pointes, ventricular tachycardia, ventricular fibrillation, vasodilation, asthma, epistaxis, pulmonary embolism, diarrhea, vomiting, dyspepsia, nausea, abdominal pain, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, stomatitis, glossitis, abdominal distension, constipation, thirst, belching, bloating, acute pancreatitis, tongue discoloration, tooth discoloration, abnormal liver function tests, bile stasis, hepatitis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyltransferase, liver failure, hepatocellular jaundice, rash, hyperhidrosis, vesicular dermatitis, pruritus, urticaria, papular rash, acne, Henoch-Schonlein purpura, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal stiffness, myalgia, rhabdomyolysis, myopathy, elevated serum creatinine, elevated serum urea, renal failure, nephritis, phlebitis at injection site, pain at injection site, inflammation at injection site, lethargy, fever, malaise, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color

This medication should be stored in a sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug’s effectiveness and safety.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle