Hupzol Capsule 30 mg (Lansoprazole Granules)

Adult dose

This medicine should be taken before meals. For patients who have difficulty swallowing the medicine, open the capsule, mix its contents with a small amount (60 mL) of orange juice or tomato juice, and administer immediately. Rinse the glass with twice or more the amount of juice to ensure the entire dose is taken, and drink immediately. Do not chew or crush the contents after opening the capsule. Adults 1. Short-term treatment of active duodenal ulcer: Administer lansoprazole 15 mg orally once daily for 4 weeks. 2. Short-term treatment of active benign gastric ulcer: Administer lansoprazole 30 mg orally once daily for 8 weeks. 3. Eradication of Helicobacter pylori to prevent recurrence of duodenal ulcer 1) Administer lansoprazole 30 mg with clarithromycin 250 ∼ 500 mg and amoxicillin 1,000 mg twice daily (every 12 hours) for 7 days. Treatment may be continued for up to 14 days if necessary. 2) Administer lansoprazole 30 mg with amoxicillin 1,000 mg three times daily (every 8 hours) for 14 days. 4. Maintenance therapy following treatment of duodenal ulcer: Administer lansoprazole 15 mg orally once daily. Comparative clinical trials did not exceed 12 months. 5. Treatment of NSAID-induced gastric ulcer: Administer lansoprazole 30 mg orally once daily for 8 weeks. Comparative clinical trials did not exceed 8 weeks. 6. Reduction of the risk of NSAID-induced gastric ulcer: Administer lansoprazole 15 mg orally once daily for 12 weeks. Comparative clinical trials did not exceed 12 weeks. 7. Short-term treatment of symptoms associated with gastroesophageal reflux disease Administer lansoprazole 15 mg orally once daily for 8 weeks. 8. Short-term treatment of erosive reflux esophagitis: Administer lansoprazole 30 mg orally once daily for 8 weeks. 9. Maintenance therapy following treatment of erosive reflux esophagitis: Administer lansoprazole 15 mg orally once daily. 10. Pathological hypersecretory conditions, including Zollinger-Ellison syndrome The lansoprazole dose for pathological hypersecretory conditions varies by patient. Treatment in adults is usually initiated at 60 mg once daily. The dose should be adjusted according to the patient's needs and may be continued for as long as it is clinically effective. Doses of 90 mg twice daily have been administered. If the daily dose exceeds 120 mg, administer it in divided doses. Elderly patients Because clearance of this medicine is reduced in elderly patients, dose adjustment is necessary. Do not exceed a daily dose of 30 mg. Patients with hepatic impairment Because metabolism and excretion of this medicine may be delayed in patients with hepatic impairment, administer with caution, including dose adjustment as needed.

Child dose

Children and adolescents 12 ∼ 17 years of age — Short-term treatment of symptoms associated with non-erosive gastroesophageal reflux disease: 15 mg once daily for 8 weeks Children and adolescents 12 ∼ 17 years of age — Short-term treatment of erosive reflux esophagitis: 30 mg once daily for 8 weeks Children 1 ∼ 11 years of age, 30 kg or less — Short-term treatment of symptoms associated with gastroesophageal reflux disease and erosive reflux esophagitis: 15 mg once daily for 12 weeks Children 1 ∼ 11 years of age, over 30 kg — Short-term treatment of symptoms associated with gastroesophageal reflux disease and erosive reflux esophagitis: 30 mg once daily for 12 weeks

This drug should not be used in patients who are allergic to certain components or have a history of hypersensitivity to benzimidazoles. Patients with allergies to penicillin and macrolide antibiotics should also use caution, and it should not be used in combination with certain cardiac medications. Women who are pregnant and patients with genetic lactose intolerance should not take this drug. Patients with a history of drug allergies, those with poor liver function, the elderly, nursing mothers, and children should take this drug with caution. Although rare, serious side effects such as severe allergic reactions, blood abnormalities, liver function impairment, severe skin conditions, and nephritis may occur, so symptoms should be closely monitored. Long-term use may lead to nutrient deficiencies such as vitamin B12 deficiency or hypomagnesemia, necessitating regular testing. This drug may slightly increase the risk of bacterial infections in the gastrointestinal tract by inhibiting gastric acid secretion; therefore, if symptoms like diarrhea persist, a doctor should be consulted. There may be interactions with other medications, so it is essential to inform healthcare staff, especially if taking antibiotics, anticoagulants, immunosuppressants, or HIV treatments. During pregnancy or breastfeeding, this drug should be avoided or discussed with healthcare providers, and safety has not been fully established for children, thus caution is needed. Elderly patients may have reduced bodily functions, so treatment should begin with a low dose and be administered carefully. In case of overdose, treatment should be sought promptly as the drug cannot be removed by hemodialysis. This drug should be kept out of reach of children, and transferring it to another container may cause a decrease in quality.

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, systemic rash, facial edema, dyspnea, shock, pancytopenia, agranulocytosis, hemolytic anemia, neutropenia, thrombocytopenia, anemia, jaundice, elevated AST, elevated ALT, toxic liver dysfunction, toxic epidermal necrolysis, Stevens-Johnson syndrome, DRESS syndrome, interstitial pneumonia, fever, cough, abnormal lung sounds, interstitial nephritis, acute renal failure, membrane colitis, hematochesia, abdominal pain, diarrhea, headache, abdominal distension, allergic reaction, back pain, weakness, candidiasis, neoplasm, chills, chest pain, edema, fever, flu-like symptoms, halitosis, infection, malaise, neck stiffness, pelvic pain, angina, arrhythmia, bradycardia, tachycardia, cerebrovascular accident, cerebral infarction, hypertension, hypotension, migraine, myocardial infarction, palpitations, vasodilation, syncope, asthma, bronchitis, increased cough, epistaxis, hemoptysis, hiccups, pneumonia, upper respiratory infection, laryngeal tumor, pulmonary fibrosis, pharyngitis, pleural disorder, respiratory disorder, rhinitis, sinusitis, wheezing, abnormal stool, enteritis, gastritis, gastrointestinal abnormalities, gastrointestinal diseases, gastrointestinal bleeding, loss of appetite, gastric stone, pyloric spasm, cholelithiasis, constipation, thirst, thirst, dyspepsia, dysphagia, belching, esophageal stricture, esophageal ulcer, esophagitis, stool discoloration, bloating, gastric nodule, gastric polyp, gastritis, upper gastrointestinal bleeding, hematemesis, increased appetite, increased salivation, anal bleeding, stomatitis, tongue disease, glossitis, gum bleeding, postprandial nausea, colitis, vomiting, nausea, diarrhea, gastric candidiasis, rectal disease, rectal bleeding, diabetes mellitus, goiter, hypothyroidism, anemia, hemorrhage, lymphadenopathy, vitamin deficiency, gout, hyperglycemia, hypoglycemia, dehydration, weight gain, weight loss, peripheral edema, bone disease, joint disease, leg cramps, arthritis, arthralgia, musculoskeletal pain, myalgia, myasthenia, ptosis, synovitis, anxiety, amnesia, unease, indifference, confusion, depression, dizziness, syncope, hallucination, hemiplegia, worsening hostility, decreased libido, increased libido, neurosis, paresthesia, abnormal thinking, convulsions, dementia, depersonalization, diplopia, hyperkinesis, hypertonia, hyposensitivity, insomnia, sleep disorder, drowsiness, tremors, acne, hair loss, pruritus, rash, urticaria, contact dermatitis, dry skin, nail disease, skin cancer, skin disease, sweating, abnormal vision, amblyopia, blepharitis, cataract, conjunctivitis, dry eyes, ear disease, eye disease, glaucoma, abnormal sense of smell, photophobia, retinal degeneration, loss of taste, blurred vision, deafness, eye pain, otitis media, taste disturbance, tinnitus, visual field narrowing, urinary disorders, renal colic, penile disease, testicular disease, urethral pain, polyuria, frequency of urination, urinary retention, menstrual irregularities, chest tenderness, chest expansion, gynecomastia, diabetes, hematuria, erectile dysfunction, renal stones, hepatotoxicity, pancreatitis, taste abnormalities, aplastic anemia, leukopenia, neutropenia, thrombotic thrombocytopenic purpura, eosinophilia, hypomagnesemia, Clostridium difficile diarrhea, fracture, myositis, erythema multiforme, acute generalized exanthematous pustulosis, speech disorder, urinary retention, elevated ALP, elevated LDH, elevated γ-GTP, weakness, hyponatremia, elevated total cholesterol, decreased total cholesterol, tongue paralysis, lip paralysis, limb paralysis, abdominal pain

This drug may be sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. Additionally, it is recommended to keep the drug at room temperature between 1°C and 30°C, avoiding excessively hot or cold places.

Appearance

A white to light brown granule-filled hard capsule with a white body and cap.

Package unit

28 capsules/bottle