Linatone M Tablets 2.5/500mg

Adult dose

The dosage of this medication is determined based on the current therapy, efficacy, and tolerance of each patient without exceeding the maximum recommended doses of the individual components of linagliptin 2.5 mg and metformin 1000 mg, administered twice daily. This medication should be taken twice daily with meals. 1. In case not currently being treated with metformin: The initial dose is 2.5/500 mg of this medication taken twice daily, 1 tablet at a time.

This medication can cause a rare but serious side effect called lactic acidosis, so caution is required. Patients with allergies to the active ingredient or component of this medication, type 1 diabetes patients, patients with severe renal impairment, and certain other patients should not use this medication. If renal function is impaired, this medication should not be administered, and patients with unstable renal function should undergo regular renal function tests. Patients with weak heart function or those who have acute heart disease should also use this medication cautiously. If iodinated contrast media is required during radiological examinations, the use of this medication should be stopped before and after the examination, and it should only be resumed once renal function is stabilized. Patients scheduled for surgery should stop taking this medication 48 hours before the surgery and only resume after normal recovery of renal function. This medication may cause hypoglycemia, so when used in conjunction with insulin or sulfonylureas, blood sugar levels should be carefully monitored. If severe abdominal pain or signs of acute pancreatitis occur during use, the medication should be discontinued immediately and the physician should be consulted. If blisters or rashes develop on the skin while taking this medication, the physician should be informed immediately, and if blistering dermatitis is suspected, the medication should be stopped. Long-term use of this medication can lead to vitamin B12 deficiency, so regular checks of vitamin B12 levels are recommended. Pregnant women or women who may become pregnant, as well as nursing mothers, should avoid using this medication and should consult with a doctor for appropriate treatment if planning for pregnancy. It is not recommended for children under 10 years old and adolescents aged 10 to 17, as safety and efficacy have not been established. Elderly patients are commonly at risk for impaired renal function, so it is advisable to periodically check renal function and administer the minimum effective dose. The risk of lactic acidosis increases when this medication is taken with alcohol; therefore, it is important to avoid alcohol consumption. There may be drug interactions; thus, patients should inform their doctor or pharmacist of any other medications they are taking. Caution is required when driving or operating machinery during treatment, so patients should closely monitor their condition.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, liver dysfunction (abnormal liver function tests, hepatitis), angina pectoris, acute myocardial infarction, unstable angina, cardiac arrest, congestive heart failure, fever, dyspnea, asthma, pneumonia, pulmonary embolism, acute renal injury, end-stage renal disease, acute cholangitis, acute cholecystitis, cholangitis, cholelithiasis, cerebral infarction, severe and disabling arthralgia, severe edema associated with increased blood pressure,

Mild side effects

• Nasopharyngitis
• hypersensitivity
• angioedema
• hypoglycemia
• taste disorders
• cough
• decreased appetite
• diarrhea
• constipation
• nausea

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. Additionally, to maintain the effectiveness of the drug, it is recommended to store it at room temperature between 1 and 30 degrees Celsius.

Appearance

Bright yellow, biconvex, oval film-coated tablet

Package unit

60 tablets (10 tablets/PTP packaging) X 6