Medication info
Candequr Tablets 8 mg (Candesartan Cilexetil)

Candequr Tablets 8 mg (Candesartan Cilexetil)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›8mg / 1 tablet
Manufacturer / importer
(주)테라젠이텍스
Appearance
Light pink, biconvex, round tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201903456 · Approved 2019.05.28 · Insurance code 671707180

Summary

Main use
Treatment of essential hypertension and heart failure (left ventricular dysfunction)
Who takes it
Adults · Children
Adult dose
For essential hypertension, the initial and maintenance dose is recommended as 8-16 mg of Candesartan Cilexetil taken orally once daily. If blood pressure is not sufficiently controlled after four weeks of treatment at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. For patients with reduced effective blood volume or renal impairment, the initial dose starts at 4 mg, while patients with liver disease should start at 2 mg once daily.
Child dose
Safety and efficacy in children and adolescents under 18 years of age have not been established.

Ingredients

Manufacturer
(주)테라젠이텍스

Efficacy & effects

Treatment of essential hypertension and heart failure (left ventricular dysfunction)

  • Essential hypertension
  • heart failure
  • impaired left ventricular systolic function
  • decreased left ventricular ejection fraction
View approved original text

This medication is used to control blood pressure in patients with essential hypertension. Additionally, it helps improve symptoms of heart failure in patients with impaired left ventricular systolic function who require adjunct therapy with ACE inhibitors or who are intolerant to ACE inhibitors.

How to take

Adult dose

For essential hypertension, the initial and maintenance dose is recommended as 8-16 mg of Candesartan Cilexetil taken orally once daily. If blood pressure is not sufficiently controlled after four weeks of treatment at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. For patients with reduced effective blood volume or renal impairment, the initial dose starts at 4 mg, while patients with liver disease should start at 2 mg once daily.

Child dose

Safety and efficacy in children and adolescents under 18 years of age have not been established.

Precautions

This medication can cause serious harm to the fetus, especially in the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. This medication should not be taken by individuals allergic to this drug or its ingredients, women who are pregnant or may become pregnant, those who are breastfeeding, and individuals with severe liver disease or bile obstruction. Patients with hereditary angioedema or a history of angioedema while using ACE inhibitors or angiotensin II receptor antagonists, as well as those with primary hyperaldosteronism, should also not take this medication. Persons with genetic disorders such as lactase deficiency, Lapp lactase deficiency, or glucose-galactose malabsorption should avoid using this drug. Elderly patients, those with hyperkalemia, patients with liver disease, individuals with certain heart valve diseases or cardiomyopathy, and those with ischemic heart disease or cerebrovascular disorders should use this medication with caution. Patients with impaired kidney function or those who have received a kidney transplant, as well as adolescents and children under 18, should be cautious. Side effects may include dizziness, back pain, and respiratory infections, and rarely serious blood disorders, liver dysfunction, muscle pain, or kidney damage may occur. Particularly in heart failure patients, hypotension, hyperkalemia, and worsening kidney function may occur, thus regular blood tests are necessary. This medication should be taken with caution if used with other antihypertensives as the blood pressure-lowering effect may be increased, and particular caution is recommended when used in conjunction with potassium-sparing diuretics or potassium supplements, as this can dangerously raise serum potassium levels, warranting careful monitoring. Women who are pregnant or planning to become pregnant should not take this medication and breastfeeding women are advised to discontinue breastfeeding when taking this medication. In case of overdose, symptoms such as hypotension, dizziness, and rapid heartbeat may occur, and immediate consultation with a healthcare provider is necessary, as this drug is not removed by hemodialysis, thus requiring appropriate emergency management. Keep out of reach of children, and avoid transferring the medication to other containers as it may affect product quality. Caution is advised as dizziness may occur when driving or operating machinery.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis,

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory tract infections, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, arthralgia, proteinuria, weakness, fever, paresthesia, dyspepsia, gastroenteritis, tachycardia, palpitations, increased creatine kinase, hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, epistaxis, anxiety, depression, drowsiness, rash, increased sweating, hematuria,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it is best to store it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance and packaging

Appearance

Light pink, biconvex, round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.