Samsung Lafutidine Tablet 10 mg

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. Clinical trials of treatment for up to 8 weeks showed that most ulcers healed within 8 weeks, although healing time may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. Clinical trials of treatment for up to 6 weeks showed that most ulcers healed within 6 weeks, although healing time may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. Clinical trials of treatment for up to 2 weeks showed that most lesions healed within 2 weeks, although healing time may vary in some patients. 4. Antibiotic combination therapy for patients with peptic ulcer disease infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose orally twice daily.

This medication should not be used in patients with hypersensitivity to its ingredients. It also contains lactose, so patients with lactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take it. Patients with a history of drug hypersensitivity, impaired liver or kidney function, those undergoing dialysis, and the elderly should use this medication cautiously. This medication can cause serious allergic reactions such as anaphylaxis or shock; therefore, if there is facial pallor, drop in blood pressure, widespread rash, or difficulty breathing during administration, treatment should be immediately halted, and appropriate medical help should be sought. Liver function impairment or jaundice may occur, so regular liver function tests should be conducted, and if abnormalities are found, discontinuation of the medication is necessary. Blood-related abnormal symptoms such as agranulocytosis or thrombocytopenia may occur, so if there are symptoms such as sore throat, fatigue, or fever, immediate consultation with a doctor is essential. Additionally, rare side effects such as skin rash, convulsions, and heart rhythm irregularities have been reported; hence, any unusual symptoms should be promptly reported to healthcare providers. Constipation, diarrhea, nausea, headache, insomnia, dizziness, warmth, facial flushing, elevated leukocyte count, increased eosinophils, decreased leukocyte count, decreased red blood cell count, decreased hematocrit, elevated ALT(GPT), elevated AST(GOT), elevated Al-P, elevated γ-GTP, elevated T-Bil, elevated LDH, elevated TTT, abnormal urinary protein, elevated BUN, and elevated serum uric acid may occur during administration, so it is important to consult a professional if symptoms are severe or persistent. This medication can mask symptoms of malignant tumors and delay diagnosis; therefore, if there are unintentional weight loss, repeated vomiting, hemoptysis, or other concerning symptoms, necessary examinations must be conducted. If gastric cancer is suspected and malignancy is confirmed after initial examinations, the medication should be discontinued, and if there is no therapeutic effect, other treatment options should be considered. Elderly patients should be closely monitored for dosage adjustments and intervals, as their physical functions may decline. Dialysis patients should start taking this medication cautiously from a low dose, as blood drug concentrations may increase. Pregnant women or women who may become pregnant should take this medication only when the benefits outweigh the risks, as determined by a physician, and breastfeeding women are advised not to take this medication due to possible secretion into breast milk. The safety in children has not been adequately established, so caution is needed in usage. This medication should be stored out of the reach of children and kept in its original container to prevent misuse or deterioration of quality. Lastly, although no carcinogenic effects were found in animal tests, some side effects have been reported at high doses; therefore, adherence to prescribed dosages and administration instructions is important.

• Shock
• symptoms of anaphylaxis
• facial pallor
• hypotension
• generalized rash
• dyspnea
• hepatic dysfunction
• jaundice
• agranulocytosis
• pharyngodynia

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, it is safest to store the drug at room temperature, between 1°C and 30°C, not in excessively hot or cold conditions.

Appearance

White circular film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle