Prucalopride 1 mg (Prucalopride Succinate)

Adult dose

Administered orally, can be taken at any time of the day regardless of meals. Adults: 2 mg once daily. Elderly over 65 years: Initial dose is 1 mg once daily, may be increased to 2 mg once daily if necessary. For patients with severe renal impairment (GFR < 30 ml/min/1.73 m2), administer 1 mg once daily. Dosage adjustment is not required for mild to moderate renal impairment.

This medication should not be used by certain patients. For instance, individuals allergic to any of the ingredients in this drug or patients with severely impaired kidney function requiring dialysis should not take it. Additionally, patients with serious intestinal issues or those genetically unable to digest lactose should also refrain from using this medication. In cases of severe kidney disease, the dosage should be reduced and used with caution, and patients with other severe health conditions such as liver or heart disease need to be careful. Particularly, patients with a history of heart rhythm issues should be especially careful when using this drug. While taking this medication, gastrointestinal issues such as headaches, abdominal pain, nausea, and diarrhea, as well as symptoms like dizziness and fatigue, may occur. These symptoms usually appear early in treatment and often diminish over time. If new symptoms like palpitations arise, consulting a doctor is essential. In cases of severe diarrhea, the effectiveness of oral contraceptives may be reduced, so it is recommended to use additional contraceptive methods. This drug has a low potential for interactions with other medications, but caution is advised when used in conjunction with certain drugs. Pregnant women are not recommended to use this medication, and women of childbearing age should use effective contraceptive methods while taking it. Breastfeeding women should also avoid using this medication. It is advisable for children and adolescents under 18 years of age not to take this drug. In case of overdose, symptoms like headaches, nausea, and diarrhea may occur, and appropriate treatment is necessary based on the symptoms. Lastly, this medication should be stored out of reach of children and protected from moisture by keeping it in its original container.

Serious side effects

• Chest discomfort
• facial swelling
• peripheral edema
• swelling
• ventricular extrasystole

Mild side effects

• Headache
• dizziness
• tremors
• palpitations
• nausea
• diarrhea
• abdominal pain
• vomiting
• dyspepsia
• rectal bleeding

This medication should be stored in a special container to protect it from light, air, and moisture. Additionally, it is recommended to keep the medication at room temperature between 1°C and 30°C for safe storage.

Appearance

White round film-coated tablet

Package unit

28 tablets (7 tablets/PTPX4)/box