Alfaroastatin Calcium Tablet 5 mg

Adult dosage

For adults with primary hypercholesterolemia, this medication can be taken at any time of day regardless of meals. The initial dose is 5 milligrams once daily; if a greater reduction in LDL cholesterol is required, the maintenance dose can be adjusted up to 10 milligrams once daily. The maintenance dose should be adjusted depending on the treatment goal and patient response, with a maximum increase up to 20 milligrams once daily at intervals of 4 weeks or more.

Children's dosage

For pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), a dose of 5 milligrams to 20 milligrams is administered once daily, and the dosage should be adjusted individually based on treatment goals at intervals of 4 weeks or more.

This medication should not be administered to certain patients. For example, it should not be used in patients with allergies to this drug, severe liver dysfunction, myopathy, severe kidney dysfunction, or women who are pregnant or breastfeeding. This drug can affect the liver and muscles; therefore, patients with a history of liver disease or those who consume excessive alcohol should undergo liver function tests before administration and be cautious. Additionally, if symptoms of muscle pain or weakness occur, they should immediately consult a doctor. This medication can interact with other drugs, so patients must inform their healthcare provider about any other medications they are taking, especially with fibrate-class medications, which require caution when used in combination. Women who could become pregnant should use appropriate contraception while taking this medication and avoid its use during pregnancy or breastfeeding. Routine liver function and muscle-related tests are recommended while taking this drug, and special caution is warranted for elderly patients or those with decreased kidney function. In the case of overdose, there is no specific antidote, so patients should seek medical help immediately for appropriate treatment and monitoring. Caution is needed while driving or operating machinery, as dizziness may occur. This medication contains lactose, so it is advised that patients with lactose intolerance avoid taking it. Finally, this medication may rarely cause serious skin reactions, liver damage, or neurological abnormalities, and any unusual symptoms should be reported to healthcare staff immediately.

Serious side effects

• Allergic reactions including urticaria and angioedema
• Stevens-Johnson syndrome
• Drug reaction with eosinophilia and systemic symptoms (DRESS)
• Chest tightness
• Difficulty breathing
• Respiratory abnormalities accompanied by cough and fever
• Jaundice
• Hepatitis
• Severe rash, blistering, skin peeling, pain in oral/ocular mucosa with high fever
• Abrupt and severe headache, thunderclap headache, seizures, confusional state, visual disturbances, paralysis

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• thrombocytopenia

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best to store it at room temperature, specifically between 1 to 30 degrees Celsius.

Appearance

Yellow round film-coated tablets

Package unit

28 tablets (14 tablets/PTPX2) - 14 tablets/PTP, 28 tablets (14 tablets/PTPX2) - 2 PTP/box