Roxitensine Tablets 150 mg (Roxithromycin)

Adult dose

Adults: Administer 150㎎ (potency) of roxithromycin orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose as appropriate according to age and symptoms.

This medication can cause severe blistering skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized pustular rash, so if symptoms such as blistering or mucosal damage occur, use should be discontinued immediately. Do not use this medication if you have allergies to antibiotics in a similar class or are taking certain other medications (terfenadine, astemizole, cisapride, pimozide, ergot alkaloids, mizolastine). Patients with poor liver function, elderly individuals, and those taking specific antibiotics should exercise caution when using this medication, and it should be used with care in individuals with heart-related issues (e.g., QT interval prolongation, arrhythmia risk). This medication may worsen symptoms in patients with myasthenia gravis, so such patients should be especially cautious. Rarely, serious allergic reactions such as anaphylactic shock may occur, so if any unusual symptoms appear, discontinue use immediately and seek appropriate medical treatment. Various side effects such as fever, rash, changes in blood cell counts, liver dysfunction, indigestion, diarrhea, pseudomembranous colitis, pneumonia, neurological symptoms (drowsiness, headaches, dizziness), taste and smell disturbances, hearing impairment, and vision disturbances may occur, so if any symptoms arise, consult healthcare professionals. This medication should be used only for the minimum necessary duration to prevent resistance, and patients with liver dysfunction should regularly monitor liver function tests and adjust dosages accordingly. Patients with poor kidney function do not require dosage adjustment, but care should be taken to avoid overdose in children. This medication may interact with other drugs, so especially inform your healthcare provider if you are taking heart medications, anticoagulants, immunosuppressants, sedatives, or digoxin. Pregnant women or those who may become pregnant should use this medication only if the benefits outweigh the risks, and during breastfeeding, it is advisable to avoid use or discontinue breastfeeding. No special dosage adjustment is necessary for elderly patients, but physical reactions should be carefully monitored. Dizziness or vision disturbances may occur, so caution is advised when operating machinery or driving. This medication should be kept out of the reach of children, and transferring it to other containers is not recommended as it may adversely affect safety and quality.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized pustular exanthema, shock, anaphylactic shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, elevated serum bilirubin, loss of appetite, nausea, vomiting, gastric discomfort, dyspepsia, stomach pain, abdominal pain, abdominal distension, diarrhea, hemorrhagic colitis, bloody stools, pseudomembranous colitis, loose stools, bronchospasm, cough, dyspnea, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, dysgeusia, ageusia, olfactory disturbance, anosmia, erythema multiforme, purpura, superinfection due to overgrowth of non-sensitive pathogens, transient hearing loss, hearing impairment, visual disturbance, blurred vision, conjunctival hyperemia, generalized malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, epistaxis, menstrual irregularities, inflammation of oral and vaginal mucous membranes, hallucinations, confusion

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is advisable to maintain the storing temperature between 1°C and 30°C to preserve the medication's effectiveness.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle