Cefotamine Dry Syrup 125mg/5mL (Cefaclor Hydrate)

Adult dose

Adults: Administer 250 mg (based on pharmacological effect) of cefaclor orally every 8 hours. In cases of severe infections (such as pneumonia) and infections with low susceptibility, the dose can be doubled. For acute gonococcal urethritis, administer 3 g of this drug and 1 g of probenecid as a single dose.

Child dose

Pediatrics: Administer 20 mg (based on pharmacological effect) per kg of body weight divided every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, a dose of 40 mg (based on pharmacological effect) per kg of body weight may be administered.

This drug works by binding to specific proteins and inhibiting the synthesis of the bacterial cell wall, thus killing the bacteria. Before using this drug, it is essential to inform if you have previously experienced severe allergic reactions or shock from this drug or similar antibiotics. Also, patients with a genetic inability to break down lactose should not use this drug due to its lactose content. Particular caution should be exercised in patients who are allergic to penicillin antibiotics or have a tendency for allergic reactions such as asthma, rashes, or hives. Patients with severely impaired kidney function or elderly patients, as well as those with poor nutritional status, should be carefully monitored while using this drug. While taking this medication, rare but severe allergic reactions, skin rashes, blood abnormalities, liver or kidney function disturbances, gastrointestinal problems, central nervous system symptoms, etc., may occur, so consult a doctor immediately if any symptoms arise. This drug must be used only for the necessary minimum period to prevent the development of resistant bacteria, and it is advisable to perform susceptibility testing for the infectious bacteria before treatment. When taken with other medications, interactions may occur; therefore, especially if you are taking medications that affect the kidneys or anticoagulants, or oral contraceptives, be sure to inform your doctor or pharmacist. Pregnant or breastfeeding women should use this drug cautiously only if necessary, and its safety has not been established for newborns or infants under one month old. Elderly patients may show adverse reactions more easily due to decreased body function, so dosage and administration intervals should be adjusted, and careful monitoring is required. During the use of this drug, some urine test results may be falsely indicated, so be sure to inform about the use of this drug during tests.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, shock, anaphylactic symptoms (generalized flushing, edema, difficulty breathing, vascular edema, paresthesia, syncope, hypertension, vasodilation), Stevens-Johnson syndrome, toxic epidermal necrolysis, agranulocytosis, granulocytopenia, pancytopenia, anemia, thrombocytopenia, aplastic anemia, hemolytic anemia, liver abnormalities (jaundice, hepatitis, AST, ALT, ALP elevation), acute renal failure, kidney damage

Mild side effects

• Rash
• itching
• fever
• swollen lymph nodes
• joint pain
• serum sickness-like reactions
• nausea
• vomiting
• diarrhea
• abdominal pain

This drug is sensitive to light, so it should be stored in a dark place, preferably at room temperature. Additionally, it should be stored in a tightly sealed container to avoid contact with air.

Appearance

Pink to red cefaclor syrup that is dissolved before use

Package unit

For oral use - 30 mL/bottle, For oral use - 150 mL/bottle