Medication info

OFLIC Tablet 100mg (Ofloxacin)

Prescription medicationTabletExpired
Ingredient · strength
Ofloxacin›10mg / 1 tablet
Manufacturer / importer
Light Pharmtech Co., Ltd.
Appearance
White to off-white round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Expired

MFDS item code 201903222 · Approved 2019.05.20

This product's status changed to Expired on 2024.05.20. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of various bacterial infections (e.g., urinary tract, respiratory, and skin infections); combination therapy for Hansen's disease
Who uses it
Adults
Adult dosage
Adults usually take 300~600 mg of ofloxacin in 2~3 divided doses daily. For Hansen's disease, take 400~600 mg of this drug in 2~3 divided doses daily. In principle, it should be used in combination with other antileprosy drugs. The dose may be adjusted as appropriate according to age and symptoms.

Ingredients

Manufacturer
Light Pharmtech Co., Ltd.

Efficacy & effects

Treatment of various bacterial infections (e.g., urinary tract, respiratory, and skin infections); combination therapy for Hansen's disease

  • Infections of complicated skin and soft tissues
  • acute otitis media
  • chronic suppurative otitis media
  • acute and chronic bacterial sinusitis
  • community-acquired pneumonia
  • acute exacerbations of chronic obstructive pulmonary disease including chronic bronchitis
  • acute pyelonephritis
  • simple acute cystitis
  • bacterial prostatitis
  • epididymitis
  • gonococcal urethritis
  • non-gonococcal urethritis
View approved original text

This medication is effective against various types of bacterial infections. It is primarily used for treating complicated skin and soft tissue infections, acute and chronic otitis media, and acute and chronic sinusitis. It is also effective for community-acquired pneumonia, acute exacerbations of chronic obstructive pulmonary disease, urinary tract infections, and bacterial gastroenteritis. It is also included in the treatment of infections of the uterus and surrounding tissues in women, various ophthalmic infections, and leprosy. However, due to the nature of fluoroquinolone drugs, significant adverse reactions may occur, so its use is recommended for patients with no other treatment options. Overall, this drug is useful in treating various bacterial infections.

Dosage and Administration

Adult dosage

Adults usually take 300~600 mg of ofloxacin in 2~3 divided doses daily. For Hansen's disease, take 400~600 mg of this drug in 2~3 divided doses daily. In principle, it should be used in combination with other antileprosy drugs. The dose may be adjusted as appropriate according to age and symptoms.

Precautions

This medication can cause tendon-related conditions such as tendonitis and tendon rupture, so it should be discontinued immediately if these symptoms appear. Additionally, it can cause peripheral neuropathy and central nervous system adverse reactions, and medical consultation is necessary if neurological symptoms arise. It should be avoided in patients with myasthenia gravis as it may worsen symptoms. The use of this drug is limited to situations where alternative treatments are unavailable for specific infections. Combining with corticosteroids increases the risk of tendon damage, so co-administration should be avoided. Patients at high risk may experience neurological side effects such as dizziness or seizures, necessitating caution. Allergic reactions or anaphylaxis may occur; if symptoms arise, treatment should be stopped immediately, and medical assistance should be sought. Regular testing and monitoring are required during long-term use due to possible effects on liver and kidney function. This drug may cause photosensitivity reactions, so exposure to strong sunlight or ultraviolet light should be avoided. It may affect blood sugar control, so diabetic patients should monitor blood sugar changes carefully. Pregnant women, women who may become pregnant, nursing mothers, and growing children and adolescents should not use this medication. Elderly patients may experience increased drug concentration due to decreased kidney function, requiring dose adjustments and careful monitoring. It may interact with other medications, so inform healthcare professionals of any current medications. In case of overdose, consult healthcare professionals immediately and seek appropriate measures, ensuring adequate hydration is important. This drug should be kept out of reach of children and should not be transferred to other containers.

Side effects

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactoid reaction, rash, itching, redness, swelling, fever, warmth, blisters, erythema, photosensitivity reaction, hematuria, acute renal failure, nephrolithiasis, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, jaundice due to cholestasis, fulminant hepatitis, membrane colitis, colitis with bloody stools, abdominal pain, frequent diarrhea, nausea, vomiting, gastric and abdominal discomfort, diarrhea, cirrhosis, loss of appetite, upper abdominal pain, dyspepsia, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal distension, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombocytopenic purpura, petechiae and ecchymoses, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, elevated ESR, insomnia, dizziness, headache, seizures, tremors, paresthesia, peripheral neuropathy, visual disturbances, auditory disturbances, hallucinations, drowsiness, irritability, sleep disorders, confusion, anxiety, depression, agitation, hypomania, delusion, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory and equilibrium sensory disorders, ataxia, aphasia, heaviness in the head, skin and mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, rhabdomyolysis accompanied by acute renal function deterioration, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequency, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, vulvar itching, menstrual irregularities, uterine cramps, genital rash in females, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever, drowsiness, nausea, dizziness, facial flushing, facial swelling, paresthesia, inaccurate speech, loss of directional sense

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that is airtight, preferably at a temperature between 1 degree and 30 degrees Celsius. Proper storage maintains drug efficacy and prevents degradation.

Appearance and packaging

Appearance

White to off-white round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.