RosuGreen Tablet 5 mg (Rosuvastatin Calcium)

Adult dosage

This medication can be taken at any time of the day regardless of meals. The initial dose is 5 mg once daily, which can be adjusted to the maintenance dose as needed. The maintenance dose is typically 10 mg once daily, where most patients are controlled at this dosage. Dose adjustments should be made based on LDL-cholesterol levels, treatment goals, and patient responses at intervals of 4 weeks or more, and it may be increased up to a maximum of 20 mg daily.

Children's dosage

For pediatric patients with familial hypercholesterolemia (ages 10 to 17), the usual dosage range is 5 mg to 20 mg once daily. The dosage should be adjusted according to the individual treatment goals.

This medication should not be used in certain patients. For example, patients with allergies to this drug, severely impaired liver function, muscle diseases, severely reduced kidney function, pregnant women, or breastfeeding women should not take this medication. This medication may affect liver function, so patients with a history of liver disease or heavy alcohol consumption should have liver function tests before administration and regular monitoring of liver enzyme levels during treatment. Symptoms such as muscle pain or weakness may occur and, in severe cases, can progress to rhabdomyolysis, which involves muscle tissue destruction, so symptoms should be reported to a physician immediately. Particularly, patients with reduced kidney function, hypothyroidism, a family history of muscle disease, elderly patients, and people who abuse alcohol are at higher risk for muscle-related side effects and should be monitored closely. This drug contains lactose, so patients with lactose intolerance should avoid taking it, and Asian patients may show higher serum drug concentrations, necessitating dosage adjustments. While taking this medication, interactions with other drugs may occur, so especially in cases of concurrent use of cyclosporine, fibrate-class drugs, certain antifungals or antibiotics, consultation with a physician or pharmacist is advised. Women of childbearing potential should use appropriate contraception, and pregnant or breastfeeding women should not take this medication. In cases of overdose, there are no specific antidotes, and appropriate treatment should be provided based on symptoms, with periodic checks of liver function and muscle enzyme levels. This medication may cause side effects such as dizziness, thus caution is needed while driving or operating machinery. Finally, if severe allergic reactions such as rash or difficulty breathing occur while taking this medication, it should be discontinued immediately, and healthcare professionals should be contacted.

Serious side effects

Hypersensitivity reactions including angioedema (including rash and severe swelling), pancreatitis, myopathy (including myositis), rhabdomyolysis, polyneuropathy, memory loss, peripheral neuropathy, severe muscle weakness, dyspnea, oculomotor weakness, thrombocytopenia, jaundice, hepatitis, Stevens-Johnson syndrome, eosinophilia with systemic symptoms drug reaction syndrome (DRESS), immune-mediated necrotizing myopathy, acute renal failure, oliguria, blood

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash and urticaria
• muscle pain
• weakness
• cough

This medication may be sensitive to air and moisture, so it should be kept in a tightly sealed container. The suitable storage temperature is room temperature between 1 to 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets (15 tablets/PTP x 2)