Acyclovir Tablets 200 mg (Acyclovir)

Adult administration

1. Treatment of herpes simplex virus infections - As acyclovir, administer 200 mg 5 times a day at 4-hour intervals for 5 days, prolonging treatment in cases of severe primary infections. - Severely immunocompromised patients or those with gastrointestinal absorption disorders may increase the dose to 400 mg or switch to intravenous administration. - Administer as soon as possible after infection; for recurrences, administer at the first sign of symptoms.

Child administration

1. Treatment of herpes simplex infections and prevention of herpes simplex infections in immunocompromised patients - Age 2 years and older: Same as adults. - Under 2 years: Administer 1/2 of adult dosage. - There is currently no definite data on the prevention of herpes simplex virus infections in patients with normal immune function.

This drug should not be used by patients who are allergic to this drug or its ingredients, or who have previously shown hypersensitivity to valacyclovir. Patients with impaired kidney function may be at higher risk of neuropsychiatric adverse reactions when using this drug, so caution is necessary. Patients with decreased liver function should also be cautious, as this medication may further worsen liver function. Infants and young children should be used with special caution, and should be administered the minimum dose only when necessary. Elderly patients may experience increased blood concentration of this medication due to reduced kidney function, and adverse reactions may occur more frequently; therefore, dosage and intervals should be carefully adjusted. While taking this medication, severe allergic reactions such as anaphylactic shock may rarely occur, so if symptoms such as low blood pressure, difficulty breathing, or chest tightness appear, stop using the medication immediately and inform medical personnel. Photosensitivity reactions, rashes, fever, vesicles, urticaria-like erythema may occur on the skin; if these symptoms develop, medication should be discontinued, and appropriate treatment should be initiated. Severe skin reactions including alopecia, erythema multiforme, Stevens-Johnson syndrome, or Lyell syndrome may occur, requiring careful observation of skin condition. Neuropsychiatric abnormalities such as altered consciousness, disorientation, concentration difficulties, aggression, hallucinations, seizures, drowsiness, tremors, anxiety, insomnia, may occur, particularly in the elderly and those with renal impairment. Abnormal kidney function may manifest as renal failure, hematuria, and proteinuria, so renal status should be monitored regularly. Effects on the blood and lymphatic system can lead to leukopenia, bleeding, and anemia; regular blood tests are advisable to monitor the condition. Liver function anomalies or jaundice, hepatitis symptoms may occur, so regular liver function tests are recommended. Gastrointestinal symptoms such as gastritis, nausea, vomiting, diarrhea, and abdominal pain may arise, and if these symptoms persist, inform medical personnel. Adequate hydration is necessary while using this medication, especially at high doses, to prevent dehydration and reduce the risk of nephrotoxicity. Disorientation may occur during treatment, so caution is advised when driving or operating hazardous machinery. Patients with renal impairment should be particularly careful. Interactions with other medications may occur, so it is advisable to consult a professional, particularly when used with drugs that affect renal function or probenecid, cimetidine, theophylline, mycophenolate mofetil. Pregnant women or those who may become pregnant should make careful decisions based on potential risks to the fetus while using this medication, and it is recommended to stop breastfeeding as this drug may be excreted in breast milk. In case of overdose, severe side effects such as coma, seizures, and renal failure may occur, so immediate medical attention should be sought, and blood concentration should be monitored.

Serious side effects

• Anaphylactic shock
• anaphylaxis-like reaction
• urticaria
• severe swelling
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• rash
• blisters

Mild side effects

• Photosensitivity reaction
• fixed drug eruption
• rash
• fever
• vesicles
• urticaria-like erythema
• alopecia
• erythema multiforme
• altered consciousness
• disorientation

This medication is sensitive to light and should be stored in containers that block light. Additionally, it is best to store the medication at room temperature between 1 degree Celsius and 30 degrees Celsius, to maintain its effectiveness and safety.

Appearance

Light blue round tablets

Package unit

30 tablets/bottle, 100 tablets/bottle