Donepezil Tablet 10 mg (Donepezil Hydrochloride Hydrate)

Adult dose

Adults: Administer 5 mg of Donepezil Hydrochloride once daily before bedtime. The dosage should be started at 5 mg for 4 to 6 weeks. After assessing clinical response during this period, it may be increased to 10 mg. If increasing to 10 mg daily, caution should be exercised regarding gastrointestinal adverse reactions. For underweight women aged 85 and older, do not exceed 5 mg daily.

Child dose

Pediatric: There is no experience using this medication in children.

This drug is primarily composed of Donepezil Hydrochloride Hydrate and is used to treat symptoms of Alzheimer-type dementia. Firstly, this medication should not be administered to certain patients. For example, it should not be used in individuals who are allergic to this medication or its components, women who are pregnant or may become pregnant, breastfeeding women, and patients with genetic lactose intolerance. Additionally, it should be used cautiously in patients with heart disease, a history of peptic ulcer, those taking non-steroidal anti-inflammatory drugs, patients with a history of asthma or obstructive pulmonary disease, patients with extrapyramidal disorders such as Parkinson's disease, and patients allergic to certain dyes contained in this medication. During the use of this medication, various adverse reactions may occur. Serious side effects reported include heart-related issues, gastrointestinal bleeding, liver function abnormalities, cerebrovascular problems, motor dysfunction, severe muscle symptoms, respiratory distress, acute pancreatitis, renal failure, and sudden death. Furthermore, various symptoms such as nausea, vomiting, diarrhea, dizziness, insomnia, hallucinations, depression, muscle pain may also occur, and if any unusual symptoms arise, it is important to consult a physician immediately. This medication can affect heart rhythm, so patients with heart disease may require regular electrocardiogram checks. Additionally, it can increase gastric acid secretion, which may exacerbate symptoms of peptic ulcers, so attention should be paid to gastrointestinal health. It may also affect driving or machinery operation abilities, so caution is advised during the initial dosing period or when changing doses. This medication can interact with other medications. In particular, its efficacy may change when taken with drugs that inhibit or induce enzymes metabolizing drugs in the liver, and the risk of side effects may increase when combined with other heart-affecting medications. Pregnant or breastfeeding women are advised not to use this medication, and if necessary, they should consult with a specialist. Safety in children has not been confirmed, so it should not be used in pediatric patients. In case of overdose, serious side effects such as nausea, vomiting, bradycardia, hypotension, and seizures can occur, and immediate medical attention is necessary. Finally, this medication should be kept out of the reach of children, and transferring it to another container should be avoided as it can cause deterioration in quality or accidents.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, coma

Mild side effects

• Nausea
• vomiting
• appetite loss
• diarrhea
• headache
• fatigue
• drowsiness
• insomnia
• dizziness
• anxiety

Store this medication in a tightly sealed container to prevent air or moisture from entering, and keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and ensure safe use.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle