Reclassin 250 mg (Clarithromycin)

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this drug to such patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, or rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: same as adults Children under 12 years: use clarithromycin dry syrup.

This medication should not be administered to certain patients, especially those who are hypersensitive to its additives or to macrolide antibiotics. In addition, it should not be given to patients with severe heart disease, impaired liver and kidney function, or to pregnant or nursing women. This medication can interact with various drugs, so if you are taking other medications, you must inform your healthcare provider. During administration, various side effects such as allergic reactions, gastrointestinal disturbances, liver dysfunction, kidney dysfunction, and skin rashes may occur, so symptoms should be monitored closely. In particular, there is a risk associated with irregular heartbeats or arrhythmias, so patients with heart disease should use this medication cautiously. Long-term use or high doses may lead to hearing loss or tinnitus, and if any abnormal symptoms occur, immediate consultation with a physician is necessary. Caution is required when administering this drug to children, the elderly, and immunocompromised patients, as dosage adjustment may be necessary. To prevent the emergence of antibiotic-resistant bacteria, it is important to take the medication only for the minimum required period. If gastrointestinal symptoms such as diarrhea or abdominal pain worsen during treatment, inform your healthcare provider immediately and discontinue the medication to receive appropriate treatment. It is safest to avoid this medication during pregnancy or lactation, and if absolutely necessary, consult with a specialist before making a decision. Lastly, caution is needed while driving or operating machinery during this medication, as dizziness or confusion may occur.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, pruritus, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal ulceration, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, elevated liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, oliguria, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, purpuric rash, increased amylase, decreased appetite, anorexia, insomnia, anxiety, irritability, auditory fever, psychotic disorder, confusional state, depersonalization, depression, disorientation, hallucinations, abnormal dreams, mania, taste disturbance, headache, loss of consciousness, movement disorder, non-vestibular dizziness, drowsiness, tremor, vestibular dizziness, hearing impairment, hearing loss, cardiac arrest, atrial fibrillation, QT prolongation on ECG, premature contractions, palpitations, vasodilation, asthma, nosebleeds, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, abnormal liver function tests, cholestasis, hepatitis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyl transferase, liver failure, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schönlein purpura, acute generalized pustular psoriasis, muscle cramps, musculoskeletal rigidity, myopathy, elevated blood urea, venous thrombophlebitis at injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased International Normalized Ratio, prolonged prothrombin time, abnormal urine color, changes in mental dosing, compulsive behavior, hypokalemia, hypoxemia

This medication is sensitive to light, so it should be stored in a container that blocks light. Additionally, it is advisable to keep the medication at room temperature between 15°C and 30°C. This helps maintain the efficacy of the medication and prevents deterioration.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle