Lifren Capsule 25 mg (Pregabalin)

Adult dose

This medication, pregabalin, is administered orally in two divided doses per day without regard to meals. 1. Neuropathic Pain 1) Peripheral neuropathic pain Adults: A starting dose of 150 mg per day may be administered. The dose may be increased to 300 mg per day after 3 to 7 days, and further increased up to a maximum of 600 mg per day at intervals of 7 days. 2) Central neuropathic pain Adults:

Child dose

There is insufficient safety and efficacy data for children under 12 years and adolescents aged 12-17; therefore, administration is not recommended.

This medication may increase the risk of suicidal thoughts or behavior; therefore, patients should consult a doctor immediately if they experience depression or mood changes during treatment. Individuals with allergies to pregabalin or any ingredients in this medication should not use it. Patients with lactose intolerance or certain hereditary diseases should not take this medication. Diabetic patients should be cautious as weight gain may necessitate adjustments in blood sugar control medication dosages. If symptoms of angioedema (such as swelling of the face or around the mouth) occur, the medication should be discontinued immediately. Elderly patients should be particularly careful at the beginning of treatment due to the increased risk of falls or injuries caused by dizziness or drowsiness. If visual disturbances or changes in eyesight occur, patients should inform their doctor. Withdrawal symptoms such as insomnia, headache, nausea, and anxiety may occur upon discontinuation, and the dosage should be gradually reduced according to the doctor's instructions. Due to the risk of drug abuse, patients with a history of mental illness or substance abuse should discuss with their doctor before taking this medication. Patients with reduced kidney function may require dosage adjustments. Patients with heart conditions should exercise caution when taking this medication. Taking this medication with opioid analgesics may significantly exacerbate central nervous system depression, so caution is necessary. Patients with weakened respiratory function or the elderly should discuss with healthcare professionals due to the increased risk of severe respiratory depression. Pregnant women should avoid this medication due to the risk of fetal malformation in early pregnancy, and women of childbearing age should use effective contraception. Nursing mothers should consult with a doctor about discontinuing breastfeeding or the medication since it may transfer into breast milk. Patients should be careful when driving or operating machinery due to the risk of accidents resulting from dizziness and drowsiness. Severe skin reactions (such as Stevens-Johnson syndrome) may occur rarely; thus, if skin rashes or unusual symptoms appear, medication should be discontinued immediately, and a doctor should be consulted. In case of overdose, confusion, drowsiness, seizures, etc., may occur, requiring emergency treatment. Keep this medication out of reach of children, and ensure it is not transferred to another container.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis.

Mild side effects

• Dizziness
• drowsiness
• confusion
• disturbance of spatial perception
• irritability
• depression
• feelings of euphoria
• decreased libido
• insomnia
• depersonalization

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it should be kept in a cool place between 15 to 30 degrees Celsius.

Appearance

A hard capsule with a pale yellow upper part and a white lower part containing white powder.

Package unit

30 capsules/bottle