Flucal Tablet 1 mg (Prucalopride Succinate)

Adult dose

This medication is administered orally and can be taken at any time of the day, regardless of meals. Adults should take 2 mg once daily. For elderly patients aged 65 and older, the initial dose is 1 mg once daily, and if necessary, it can be increased to 2 mg once daily. Patients with severe renal impairment and severe liver impairment should take 1 mg once daily. Patients with mild to moderate renal and liver impairment do not require dose adjustments.

This medication should not be used in certain patients. Patients who are allergic to the active ingredient or excipients, patients with severely impaired kidney function, patients with disorders of bowel function or structure, and patients with a genetic condition that prevents lactose digestion should not take this medication. The dosage of this medication should be reduced and administered cautiously in patients with severe renal impairment. In addition, caution should be exercised when administering this medication to patients with significant comorbid conditions such as liver disease, cardiovascular disease, pulmonary disease, or neurological abnormalities, as safety has not been adequately confirmed. Patients with a history of cardiac arrhythmias or ischemic heart disease should also be careful when using this medication. For patients with severely impaired liver function, it is recommended to reduce the dosing. Caution is needed when this medication is used in conjunction with drugs that can prolong the QT interval, which is an electrical property of heartbeats. Gastrointestinal symptoms such as headache, abdominal pain, nausea, and diarrhea may commonly occur with this medication, and these symptoms typically arise at the beginning of treatment and diminish over time. Palpitations, dizziness, and fatigue have also been reported, so patients should consult with healthcare professionals if these symptoms occur. Severe diarrhea may reduce the effectiveness of oral contraceptives, so it is advisable to use additional contraceptive methods. This medication has a low potential for interactions with other drugs; however, caution is warranted when taken with certain antifungal medications or some heart-related drugs. It is not recommended to use this medication during pregnancy, and women of childbearing age should use effective contraception while taking it. It is also not recommended for breastfeeding women to take this medication. This medication should not be used in children or adolescents under 18 years old. Overdose may cause symptoms such as headache, nausea, and diarrhea, and appropriate treatment may be needed depending on the symptoms. This medication may cause dizziness and fatigue on the first day of administration, so caution should be exercised when driving or operating machinery. This medication should be stored out of reach of children and kept in its original container to avoid moisture.

Serious side effects

Palpitations (heart palpitations), chest discomfort, injury, toxicity, and procedural complications (thermal burns), ventricular ectopic contractions, facial paralysis

Mild side effects

• Headache
• dizziness
• tremors
• palpitations
• nausea
• diarrhea
• abdominal pain
• vomiting
• dyspepsia
• rectal bleeding

This medication should be stored in a container that is protected from light and air, and it should be kept away from humid places. It is also advisable to store the medication at room temperature between 1°C and 30°C.

Appearance

White to off-white round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu * 2)