Jinetil Tablet 250 mg (Cefuroxime Axetil)

Adult dose

For optimal absorption, take after meals. Adults and children 12 years of age and older Most infections: 250mg twice daily. Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms: 500mg twice daily. Urinary tract infections: 250mg twice daily. Uncomplicated gonorrhea: Administer 1g as a single dose. Lyme disease: 500mg twice daily for 14 days (10~21 days). Patients with renal impairment: In patients with significantly impaired renal function, it is recommended that the dose of cefuroxime be reduced as follows to compensate for delayed elimination. ≥ 30 mL/min/1.73m2: No dosage adjustment required (standard dose: 125mg-500mg twice daily) 10 - 29 mL/min/1.73m2: Administer a standard single dose every 24 hours < 10 mL/min/1.73m2: Administer a standard single dose every 48 hours Patients receiving hemodialysis: Administer an additional standard single dose at the end of each dialysis session

Child dose

Infants and children under 12 years of age, most infections: 125mg twice daily. Otitis media in children 2 years of age and older, severe infections: 250mg twice daily. Infants and children under 12 years of age, Lyme disease: 250mg twice daily for 14 days (10~21 days). Infants under 3 months of age: Experience with use is limited.

This medication is a cephalosporin antibiotic and should not be used in patients with a known allergy to this drug class. Patients with a history of hypersensitivity reactions to penicillin or other beta-lactam antibiotics, severely impaired renal function, and those who have difficulty taking medications orally or elderly patients should be administered cautiously. Mild adverse reactions are common when taking this medication, and serious skin reactions or blood abnormalities, or liver or kidney dysfunction may occur infrequently. Consult a healthcare professional immediately if abnormal symptoms manifest. To prevent the emergence of antibiotic-resistant bacteria, it is important to confirm the susceptibility of the infecting organism and to administer the drug only for the required duration. During administration, allergic reactions or shock symptoms may occur, and if such symptoms arise, discontinue use immediately and seek appropriate treatment. This medication may cause excessive growth of fungi such as Candida, and caution should be exercised when using it for extended periods regarding non-susceptible organisms. If gastrointestinal symptoms such as diarrhea or abdominal pain are severe or persistent, suspect pseudomembranous colitis and discontinue treatment immediately. For pregnant or breastfeeding women, the safety of this medication has not been established, and it should be used cautiously only when necessary, as the drug may be transmitted through breast milk. For children, safety has not been established in infants under 3 months old, and due to the bitter taste of the tablet, using a dry syrup form is preferable. Elderly patients may experience more side effects due to decreased body function; thus, dosage and administration intervals should be adjusted, and their condition should be closely monitored. This medicine may interact with other drugs, so caution should be taken when used with diuretics, aminoglycoside antibiotics, probenecid, antacids, and it can reduce the efficacy of oral contraceptives. Dizziness may occur when driving or operating machinery, so caution is advised. In case of overdose, symptoms like seizures may appear due to central nervous system stimulation, and blood dialysis or peritoneal dialysis can help lower drug concentration.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• anemia
• hemoglobin decrease
• hematocrit decrease
• hemolytic anemia

Store this medication in a sealed container to prevent air from entering and keep it in a cool place below 25 degrees Celsius. Doing so will help maintain the effectiveness of the drug.

Appearance

This medicine is a white to off-white rectangular film-coated tablet.

Package unit

100 tablets (10 tablets/PTP) × 10