Medication info
Olaprazole 10mg (Lansoprazole)

Olaprazole 10mg (Lansoprazole)

Prescription medicationTablet
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Dongkwang Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201902331 · Approved 2019.04.16 · Insurance code 645906520

Summary

Main use
Treatment of gastrointestinal disorders (including ulcers and gastritis), pre-anesthetic medication, and combination therapy for Helicobacter pylori eradication
Who uses it
Adults
Adult dosage
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing time may occasionally vary among patients. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine orally on 2 occasions (before bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Ingredients

Manufacturer
Dongkwang Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (including ulcers and gastritis), pre-anesthetic medication, and combination therapy for Helicobacter pylori eradication

  • Gastric ulcers
  • duodenal ulcers
  • gastric mucosal lesions from acute gastritis
  • chronic gastritis
  • peptic ulcers
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat gastric ulcers and duodenal ulcers. It also helps improve gastric mucosal lesions caused by acute gastritis and chronic gastritis. It is effectively used in combination with antibiotics for patients with peptic ulcers caused by Helicobacter pylori infection. It is also used before anesthesia for surgeries or examinations, and is effective in treating gastroesophageal reflux disease. It is used to treat and improve various gastrointestinal-related disorders.

Dosage and Administration

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although the healing time may occasionally vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although the healing time may occasionally vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although the healing time may occasionally vary among patients. 4. Concomitant antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10mg of lafutidine orally on 2 occasions (before bedtime on the day before surgery and 2 hours before administration of anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Precautions

This medication should not be used in patients who are hypersensitive to any ingredient in this medication. Additionally, since this medication contains lactose, it should not be administered to patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Patients with a history of drug hypersensitivity, impaired liver or kidney function, patients on dialysis, and elderly patients should exercise special caution when using this medication. Severe allergic reactions or anaphylaxis may occur when using this medication. If symptoms such as facial pallor, low blood pressure, or difficulty breathing appear, the drug administration should be immediately stopped and appropriate treatment should be sought. Liver function impairment or symptoms of jaundice may occur, so liver status should be closely monitored, and drug administration should be stopped if abnormalities arise. Symptoms of blood cell reduction, such as sore throat, general malaise, fever, etc., may occur, so drug administration should be immediately stopped if these symptoms manifest. Rare side effects reported with similar medications include blood cell reduction, convulsions, interstitial nephritis, skin and mucous membrane damage, muscle damage, and cardiac conduction abnormalities; therefore, any abnormal symptoms should be closely monitored. Side effects may occur in various systems including the gastrointestinal, central nervous, circulatory, hematologic, hepatic, and renal systems, so medical consultation should be sought if symptoms appear. Particularly in cases where malignant tumors are suspected, symptoms may be alleviated by this medication, resulting in delayed diagnosis; therefore, tests should be conducted if symptoms such as weight loss, recurrent vomiting, or hematemesis are present. Elderly patients may require careful monitoring of drug dosage and administration intervals due to decreased bodily function. Patients on dialysis may have increased blood concentrations of this medication, so starting with a low dose and careful administration is recommended. Pregnant women or women of childbearing potential should use this medication only when the benefits outweigh the risks as determined by a physician, and breastfeeding women should avoid this medication due to potential secretion into breast milk. The safety in pediatrics has not been established, so caution is required in its use. This medication should be stored out of reach of children and kept in the original container to prevent misuse or degradation of quality.

Side effects

Shock

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.