Donepezil Hydrochloride Tablets 10 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

Administer 5 mg of donepezil hydrochloride once daily before bedtime. For 4 to 6 weeks, administer a 5 mg dosage, and after evaluating clinical responses during this period, it can be increased to 10 mg. When increasing to a daily dosage of 10 mg, caution should be exercised regarding gastrointestinal side effects. Women over 85 years old who are underweight should not exceed 5 mg daily and require careful monitoring.

Child dose

No experience of use in children.

This medication contains donepezil hydrochloride as its main ingredient and is used for the treatment of symptoms of Alzheimer's type dementia. This medication should not be administered to certain patients, including those who have allergies to donepezil hydrochloride or any components of this medication, women who are pregnant or may become pregnant, and nursing mothers should avoid taking this medication as well. Furthermore, patients with lactose intolerance or genetic lactose metabolism disorders should not take this medication. Patients with heart disease, a history of peptic ulcers or currently taking non-steroidal anti-inflammatory drugs, those with asthma or a history of obstructive pulmonary disease, and patients with extrapyramidal disorders such as Parkinson's disease should use this medication cautiously. This medication can cause various side effects, such as irregular heartbeats, gastrointestinal bleeding, bronchospasm, and movement disorders, so caution is necessary. If serious symptoms such as fainting, heart problems, gastrointestinal bleeding, liver function abnormalities, seizures, muscle abnormalities, or breathing difficulties occur while taking this medication, consult a healthcare professional immediately. Additionally, various side effects such as nausea, vomiting, diarrhea, dizziness, insomnia, hallucinations, anxiety, depression, and others may occur, so it is important to closely monitor any changes in symptoms. This medication may affect heart rhythm, so patients with heart disease may require regular electrocardiogram (ECG) examinations. Furthermore, it can increase stomach acid secretion and worsen peptic ulcers, so it is important to periodically check gastrointestinal health. Be cautious when performing complex tasks such as driving or operating machinery, as this medication can cause dizziness or fatigue, especially during the initial dosage or when changing doses. This medication can interact with various drugs, so if you are currently taking any other medications, be sure to inform your healthcare provider. Caution is especially advised if you are taking heart medications, antibiotics, antidepressants, antipsychotics, or other cholinergic medications. Pregnant or nursing women should avoid this medication, and if it's necessary, a cautious decision should be made after consulting a specialist. Safety for use in children has not been established, so it should not be administered to children. In the case of an overdose, symptoms such as nausea, vomiting, severe muscle weakness, and breathing difficulties may occur, and emergency treatment should be sought immediately, with atropine possibly being used as an antidote. Keep this medication out of reach of children and avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blistering, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities plus cough & fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and very severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary retention

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• dizziness
• insomnia
• hallucinations
• excitement

Store this medication in an airtight, tightly closed container, in a safe temperature range between 1 to 30 degrees Celsius at room temperature. This storage method will help maintain the medication's effectiveness and prevent degradation.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle