Medication info

Joongheon Clarithromycin Tablet 500 milligrams

Prescription medicationTabletExpired
Ingredient · strength
Clarithromycin›500mg / 1 tablet
Manufacturer / importer
Joongheon Pharmaceutical Co., Ltd.
Appearance
Yellow oval film-coated tablet
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Expired

MFDS item code 201902231 · Approved 2019.04.11

This product's status changed to Expired on 2024.04.11. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter eradication
Who uses it
Adults · Children
Adult dosage
Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7~14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).
Children's dosage
Children 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

Ingredients

Manufacturer
Joongheon Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of respiratory and skin infections, mycobacterial infections, and Helicobacter eradication

  • Bronchitis
  • pneumonia
  • pharyngitis
  • sinusitis
  • skin and soft tissue infections
  • mycobacterial infections
  • duodenal ulcers
View approved original text

This medication is an antibiotic effective against various bacteria. It is used for lower respiratory infections such as bronchitis or pneumonia and upper respiratory infections such as pharyngitis and sinusitis. It is also effective for treating skin and soft tissue infections. It is used for mycobacterial infections, particularly those caused by Mycobacterium avium and Mycobacterium intracellulare. Additionally, it aids in the eradication of Helicobacter pylori in patients with duodenal ulcers. Overall, this medication is used to treat a variety of infectious diseases.

Dosage and Administration

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7~14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days in these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).

Children's dosage

Children 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

Precautions

This medication should not be used by patients who are allergic to specific components or have had hypersensitivity reactions to macrolide antibiotics. It should also not be administered to patients with specific cardiac diseases or severe liver and kidney dysfunction, pregnant or breastfeeding women. Since this medication is excreted through the liver and kidneys, caution is needed for patients with weakened liver or kidney function. Careful administration is required for patients at risk for cardiac arrhythmias and the elderly. There may be many interactions when used with other medications, so it is essential to inform healthcare professionals about any medications being taken. This medication can rarely cause severe allergic reactions or adverse reactions to the liver, kidneys, skin, or nervous system; therefore, if symptoms appear, it is crucial to consult with healthcare professionals immediately. To prevent antibiotic resistance, it is important to adhere to the appropriate dosage and duration for the infected area. If diarrhea or abdominal pain persists during treatment, close observation is necessary due to the potential for serious side effects like pseudomembranous colitis. Use during pregnancy or breastfeeding should be avoided if possible, and if necessary, consultation with a specialist is recommended. In children and the elderly, special care must be taken to adjust dosage and duration appropriately. In cases of overdose, gastrointestinal disorders or neurological symptoms may occur, so immediate attention from a medical facility is necessary. This medication should be stored at room temperature, away from direct sunlight, and not refrigerated.

Side effects

Shock, anaphylactic symptoms, shortness of breath, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, tooth discoloration, pancreatitis, increased amylase, taste disturbance, decreased appetite, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucination, psychosis, depersonalization, convulsions, tremor, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, lethargy, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized exanthematous pustulosis, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea, nephritis, venous inflammation at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated alkaline phosphatase levels, elevated lactate dehydrogenase levels, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, soft tissue inflammation, candidiasis, gastroenteritis, infection, vaginitis, leukopenia, neutropenia, thrombocytosis, eosinophilia, agranulocytosis, thrombocytopenia, anaphylactoid reaction, hypersensitivity, decreased appetite, insomnia, nervous hyperactivity, noise intolerance, psychotic disorder, state of confusion, abnormal dreams, mania, vestibular vertigo, hearing impairment, cardiac arrest, atrial fibrillation, ectopic beats, palpitations, vasodilation, asthma, nasal bleeding, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, cholestasis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyltransferase, hepatocellular jaundice, vesicular dermatitis, papular rash, acne, Henoch-Schönlein purpura, myalgia, elevated blood creatinine, elevated blood urea, renal failure, nephritis, venous inflammation at the injection site, pain at the injection site, inflammation at the injection site, lethargy, fever, weakness, chest pain, chills, fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that can block light. It is important to maintain a storage temperature between 15 to 30 degrees Celsius.

Appearance and packaging

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.