Selekocapsule 200 Milligrams (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be taken regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg per dose twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg per dose twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, consider another treatment. 4. Acute pain and primary dysmenorrhea: The initial recommended dose is 400 mg of celecoxib; if necessary, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastric bleeding in those who consume three or more alcoholic beverages daily, so consultation with a doctor or pharmacist is essential. This medication may increase the risk of thrombotic cardiovascular events such as heart attacks or strokes; thus, it should only be used at the minimum effective dose and for the shortest duration possible. Immediate consultation with healthcare providers is necessary if cardiovascular symptoms appear. Gastrointestinal issues such as ulcers, bleeding, or perforation may occur, particularly in the elderly or individuals with a history of gastrointestinal disorders. This medication should not be administered to individuals with specific allergic reactions, severe liver or kidney disorders, active peptic ulcers, heart failure, or pregnant women. Individuals with weakened liver or kidney function, asthma, hypertension, heart failure, and diabetes need to be particularly cautious when taking this medication, requiring regular check-ups and monitoring. Dizziness or drowsiness may occur while taking this medication, so care should be taken when driving or operating machinery. This medication can interact with several drugs; therefore, inform healthcare providers of any other medications being taken, particularly blood pressure medications, anticoagulants, antidepressants, and diuretics. Women who are pregnant or planning to become pregnant should avoid this medication due to potential risks to the fetus, and breastfeeding women should determine usage in consultation with a professional. The safety and effectiveness of this medication in children and adolescents have not been established, so it is advisable not to use it. Elderly individuals may experience reduced kidney, liver, and heart function, so special monitoring and caution are necessary when taking this medication. Regular blood tests and liver and kidney function tests should be performed to catch any adverse signs early when this medication is used for an extended period. Overdose may result in symptoms such as nausea, vomiting, drowsiness, and gastric bleeding, requiring immediate medical attention. There is no specific antidote, so treatment will be symptomatic based on observed signs. This medication should be kept out of reach of children, and it is advisable not to transfer it to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbances, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute kidney failure, interstitial nephritis, headache, leg cramps, hypertonia, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reactions, angioedema, hallucinations, exacerbation of epilepsy, upper respiratory tract infections, herpes zoster, wound infections, gingivitis, herpes simplex, shingles, bacterial infections, fungal infections, soft tissue infections, viral infections, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic changes of the mammary glands, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, elevated creatinine, increased alkaline phosphatase, weight gain, anorexia, elevated LDH, hypoglycemia, hyponatremia, synovial cysts, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reactions, skin nodules, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute kidney failure, interstitial nephritis, menstrual disorders, chest pain, anaphylactic reactions, hallucinations, intracerebral hemorrhage, aseptic meningitis, anosmia, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitive reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute kidney failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microlesion glomerulonephritis

This medication should be stored in a sealed container to prevent air or moisture from entering, preferably in a cool place between 15 to 30 degrees Celsius. This will help maintain the medication's effectiveness over time.

Appearance

White capsules filled with a white to slightly yellow powder, with yellow stripes on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle