Rabeprazole Sodium Tablet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcer and duodenal ulcer: Administer 10 mg orally once daily; dosage can be increased to 20 mg orally once daily depending on symptoms. Treatment course lasts up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks; if treatment fails after 8 weeks, an additional course of 10 mg or 20 mg for another 8 weeks can be provided.

This medication should not be used in certain patients. First, individuals who are allergic to this medication or its components, or have experienced hypersensitivity reactions to benzimidazole derivatives should avoid administration. Additionally, those with allergies to penicillin or macrolide antibiotics, used in conjunction with this medication for the eradication of Helicobacter pylori, should not use it. In particular, pregnant or nursing women taking certain cardiac medications or drugs such as atazanavir or rilpivirine should not take this medication. Patients with poor liver function, the elderly, or those with a history of hypersensitivity reactions should be administered this drug cautiously. This medication can cause various side effects, which require attention. Allergic reactions such as skin rashes, hives, and itching may occur, and if these symptoms arise, medication should be discontinued immediately. Blood-related abnormal symptoms may also occur, so regular blood tests are advisable. Liver function abnormalities or jaundice symptoms may occur, thus liver function tests should also be conducted regularly. It may affect the heart or blood vessels leading to hypertension, myocardial infarction, or arrhythmias, so cardiovascular symptoms should be monitored closely. Gastrointestinal symptoms such as diarrhea, abdominal pain, and nausea may occur, while neurological symptoms such as headaches, dizziness, and insomnia have been reported. Abnormal signs may appear in various areas including the respiratory system, musculoskeletal system, skin, eyes, and urinary system, so if there are any abnormal signs, immediate consultation with a healthcare professional is necessary. Long-term use of this medication may increase the risk of fractures related to osteoporosis and lead to hypomagnesemia, so magnesium levels should be checked periodically. This medication strongly suppresses gastric acid secretion, thus there may be a slight increase in the risk of gastrointestinal bacterial infections. If diarrhea persists, infection with Clostridium difficile should be confirmed. Caution should be exercised when driving or operating machinery as drowsiness may occur. This medication may interact with other drugs, so especially when taking it alongside warfarin, methotrexate, antibiotics, antivirals, etc., consultation with a doctor or pharmacist is essential. Women who are pregnant or breastfeeding should not take this medication, and due to insufficient safety data, it should also be avoided in those planning to become pregnant. Elderly individuals may experience adverse reactions more readily due to decreased liver function, so they should take it cautiously while monitoring symptoms. Safety in pediatric patients has not been established, so it is not used in children. This medication should not be chewed or crushed, and tablets should be swallowed whole; it should also be stored out of reach of children and not transferred to another container. There is no specific antidote for overdose, so appropriate treatment should be received depending on symptoms, and medical assistance should be sought promptly.

Serious side effects

Hives, severe swelling, chest tightness, cold sweat, pallor, severe rash or blistering with high fever, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory issues accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme dizziness, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, markedly reduced urinary output,

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and at room temperature between 1 to 30 degrees Celsius. Storing it this way can maintain the medication's efficacy and prevent deterioration.

Appearance

Pale yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/Alu Alu packaging x 2)