Marcrox Tablets (Roxithromycin)

Adult dose

Adults: Administer roxithromycin 150㎎ (potency) orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. The dose may be adjusted according to age and symptoms.

This drug may rarely cause severe skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis; therefore, if symptoms such as blistering of the skin or mucosal damage occur, the medication should be discontinued immediately. Patients with an allergy to this drug or who have had hypersensitivity reactions to similar antibiotics should not take this medication. Additionally, it should not be used in patients taking certain medications, as serious side effects may occur with terfenadine, astemizole, cisapride, pimozide, ergot alkaloids, or mizolastine. Patients with poor liver function or the elderly should use this drug cautiously, and care is needed when taken in conjunction with other antibiotics, as there may be overlapping effects or resistance. This drug can also prolong the QT interval related to heartbeats, so patients with heart disease or those taking certain heart medications must consult their physician. This drug can cause various side effects, including severe allergic reactions, blood abnormalities, liver dysfunction, gastrointestinal issues, pneumonia, neurological symptoms, sensory disturbances, and skin rashes; if any abnormal symptoms appear, they should inform medical personnel immediately. Long-term use of this drug requires taking it only for the necessary duration to prevent resistant strains from developing. Patients with impaired liver function should have their doses adjusted with regular liver function tests. No special dose adjustments are needed for patients with poor kidney function. This drug may interact with other medications, particularly those affecting the heart or anticoagulants, immunosuppressants, sedatives, etc.; therefore, patients must inform their healthcare provider of any medications they are currently taking. Women who are pregnant or may become pregnant should carefully weigh the risks and benefits of taking this medication, and breastfeeding mothers should avoid taking it or discontinue breastfeeding if possible. The elderly may experience a prolonged half-life of this drug, but generally, no adjustments to dosage are necessary. If symptoms like dizziness or blurred vision occur when taking this medication, it is wise to avoid operating machinery or driving. Finally, this medication should be kept out of reach of children, and care must be taken not to transfer it to other containers as this may lead to a decrease in quality or accidental risks.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized pustular rash, shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, increased serum bilirubin, loss of appetite, nausea, vomiting, dyspepsia, gastric pain, abdominal pain, abdominal distension, diarrhea, colitis, loose stools, hemorrhagic colitis, pancreatitis, bronchospasm, cough, dyspnea, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, dysgeusia, ageusia, olfactory disturbance, loss of smell, erythema multiforme, purpura, superinfection due to overgrowth of non-susceptible pathogens, transient hearing loss, hearing impairment, visual disturbances, blurred vision, conjunctival injection, general fatigue, weakness, palpitations, QT prolongation, ventricular tachycardia, joint pain, epistaxis, abnormal menstruation, inflammation of oral and vaginal mucosa, hallucinations, confusion

This drug should be stored in a tightly sealed container to prevent air from entering, at a temperature between 1 and 30 degrees Celsius at room temperature. Storing it this way can maintain the drug's effectiveness and prevent deterioration.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle