Glimepidide Tablets (Glimepiride)

Adult dose

Dosage should be adjusted for each patient individually. Take without chewing with more than 1/2 cup of water. Administer orally once a day, either before breakfast or immediately before the first meal. It is crucial not to skip meals after taking this medication. 1) Initial dose for monotherapy starts at 1 mg of glimepiride taken once daily, increasing by 1 mg at intervals of 1-2 weeks. Generally, effects beyond 4 mg are minimal.

This medication should not be used in patients with insulin-dependent diabetes or those in a diabetic ketoacidosis or coma state. Additionally, individuals allergic to this medication, its components, sulfonylureas, or sulfonamides should avoid taking it. There is no experience in using this medication in patients with severe liver or kidney damage, so a switch to insulin therapy is recommended. Women who are pregnant or may become pregnant, as well as lactating women, should not take this medication. Patients with severe infections, those undergoing surgical procedures, or those with severe trauma may require insulin therapy, so caution is warranted. When experiencing gastrointestinal disorders such as diarrhea or vomiting, the risk of hypoglycemia may increase due to impaired food absorption. This medication contains lactose, so individuals with lactose intolerance or specific genetic metabolic disorders should not take it. In the first week of dosing, the risk of hypoglycemia is high, so blood sugar levels should be checked frequently, and careful monitoring is necessary. Special caution should be taken in the elderly, those with poor nutritional status or irregular meals, those who frequently consume alcohol, and those with diminished liver or kidney function. This medication can cause hypoglycemia, so if symptoms such as headache, severe hunger, vomiting, fatigue, confusion, drowsiness, or decreased consciousness occur, immediate action should be taken. Visual disturbances, gastrointestinal disorders, liver dysfunction, blood abnormalities, and allergic reactions may occur, so healthcare professionals should be informed of any symptoms. In the event of hypoglycemia, quick recovery can usually be achieved by consuming sugar, so it is advisable to always carry some sugar. When taking this medication, adherence to dietary and exercise regimens is crucial, and it is important to stick to the prescribed dosages. Taking this medication with other drugs may affect blood sugar control, so all concurrently taken medications should be disclosed to healthcare professionals. For pregnant or lactating women, switching to insulin therapy is considered safer. In cases of overdose, severe hypoglycemia may occur, necessitating immediate emergency treatment, and close monitoring in a hospital for at least 1-2 days thereafter is needed.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, hypotension, shock, skin and mucous membrane syndrome (Stevens-Johnson syndrome), anaphylaxis, angioedema, liver dysfunction (including liver failure), jaundice, seizures, loss of consciousness, coma, severe blood abnormalities (including thrombocytopenic purpura), severe hypoglycemia, severe allergic reactions.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased agility or activity

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. Doing so will help preserve the medication's effectiveness and safety for a longer period.

Appearance

Green oblong tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 500 tablets/bottle