Clarithromycin 250 mg Tablets

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily; for severe infections, administer 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, or rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for a further 14 days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14) and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: Same as adults For children under 12 years, use clarithromycin dry syrup.

This drug should not be administered to patients with specific allergic reactions. In particular, it must not be used if allergic to this drug's components or similar antibiotics. Patients with arrhythmia or cardiovascular diseases should be cautious when using this drug. Patients with severely impaired liver or kidney function should also exercise caution when administering. It is safer for pregnant or breastfeeding women not to take this drug. This drug has many drug interactions, so it's essential to inform the prescribing doctor of any medications being taken. Caution is especially needed when co-administered with certain heart medications, anticoagulants, anticonvulsants, and immunosuppressants. During the use of this drug, if allergic symptoms or severe side effects occur, consult a doctor immediately. Prolonged or high-dose use may lead to hearing loss or tinnitus, requiring caution. Dose adjustments may be needed for children, the elderly, and patients with impaired liver or kidney function. To prevent antibiotic resistance, it should only be taken for the prescribed duration as directed by a healthcare provider. If gastrointestinal disturbances such as diarrhea or abdominal pain are severe, discontinue the drug and consult medical staff. This drug may cause dizziness or confusion when driving or operating machinery, so caution is advised.

Shock, anaphylactic symptoms, dyspnea, convulsions, redness, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral erosions, upper abdominal pain, thirst, teeth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal rigidity, myopathy, elevated serum creatinine, elevated blood urea, nephritis, venous thrombophlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, abdominal bloating

This drug is sensitive to light, so it should be stored in a container that blocks light. Additionally, it is recommended to store the medication at room temperature between 1°C and 30°C. Storing it this way helps maintain the drug's effectiveness safely.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle