Simvastatin 20mg Tablets

Adult dose

The recommended initial starting dose is 40 mg of simvastatin per day. The usual initial starting dose is recommended to be 20 mg taken once daily at bedtime. For patients with mild to moderate hypercholesterolemia, starting with 10 mg may be appropriate. It is recommended to administer 5 to 40 mg once daily at bedtime. Prior to initiation of therapy, the initial LDL-cholesterol level needs to be considered.

Child dose

The recommended initial dosage for pediatric patients (ages 10 to 17) with heterozygous familial hypercholesterolemia is 10 mg once daily at bedtime. The recommended dosage range is 10 to 40 mg daily with a maximum recommended dosage of 40 mg.

This medication is used to lower cholesterol levels in the blood. Caution is advised while taking this medication as there is a risk of muscle-related issues. Especially when taking high doses or concomitant medications, serious muscle damage such as myopathy or rhabdomyolysis may occur. If symptoms such as muscle pain, weakness, or tenderness occur, consultation with a doctor is essential. Additionally, this medication may impact liver function, so patients with liver disease or elevated liver enzymes should not take it. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. It may interact with specific antifungals, antibiotics, and immunosuppressants, increasing the risk of side effects; therefore, it is essential to inform the doctor about any other medications being taken. Elderly patients and women are at a higher risk of developing myopathy, and extra caution is advised during usage. Regular blood tests for monitoring liver function and muscle status are recommended while on this medication. In case of overdose, seek immediate hospital care for appropriate treatment. Lastly, this medication should be kept out of reach of children and should be stored in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, severe skin reaction, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, jaundice, extreme lethargy throughout the body, liver dysfunction (jaundice), sudden

Mild side effects

• Abdominal pain
• weakness
• constipation
• diarrhea
• dyspepsia
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is safe to store at room temperature between 1°C and 30°C. Therefore, it should be kept in a cool and dry place until use, avoiding direct sunlight or high temperatures.

Appearance

Brownish yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle